Mental Health Book

Disease Complications

Information Resources


Major Depression Differential Diagnosis

Aka: Major Depression Differential Diagnosis, Organic Causes of Major Depression
  1. Causes: Drug-Induced
    1. See Medications Predisposing to Depression
  2. Causes: Endocrine and Metabolic
    1. Adrenal disease
      1. Cushing's Disease
      2. Addison's Disease
      3. Pheochromocytoma
    2. Thyroid disease
      1. Hypothyroidism
      2. Hyperthyroidism
    3. Parathyroid Disease
      1. Hypoparathyroidism
      2. Hyperparathyroidism
    4. Diabetes Mellitus
    5. Electrolyte disturbance
      1. Serum Sodium disturbance
      2. Serum Potassium disturbance
      3. Serum Calcium disturbance
      4. Hypoglycemia
    6. Carcinoid
    7. Ovarian Failure (Menopause)
    8. Testicular Failure
    9. Renal Failure or Uremia
    10. Heavy Metal Poisoning
  3. Causes: Infectious Disease
    1. Hepatitis
    2. Herpes Simplex VirusEncephalitis
    3. HIV Infection or AIDS
    4. Mononucleosis
    5. Syphilis
    6. Tuberculosis
    7. Lyme Disease
    8. Encephalitis
    9. Influenza
  4. Causes: Hematology and Oncology
    1. Brain Tumor
    2. Pancreatic Cancer
    3. Breast Cancer
    4. Colon Cancer and other gastrointestinal cancer
    5. Gynecologic cancer
    6. Hematologic Malignancy
  5. Causes: Neurologic Causes
    1. Cerebrovascular Accident (CVA)
    2. Huntington's Chorea
    3. Multiple Sclerosis
    4. Normal Pressure Hydrocephalus
    5. Parkinson's Disease
    6. Alzheimer's Disease
    7. Subdural Hematoma
    8. Narcolepsy
    9. Wilson's Disease
  6. Causes: Cardiovascular Disease
    1. Congestive Heart Failure
    2. Cerebral ischemia
    3. Cardiomyopathy
    4. Myocardial Infarction
  7. Causes: Nutritional Deficiency
    1. Macrocytic Anemia
      1. Folate Deficiency
      2. Vitamin B12 Deficiency
    2. Microcytic Anemia
      1. Iron Deficiency Anemia
    3. Other B Vitamin Deficiency
      1. Pyridoxine Deficiency (Vitamin B6)
      2. Riboflavin Deficiency (Vitamin B2)
      3. Thiamine deficiency (Vitamin B1)
  8. Causes: Psychiatric
    1. Other disorder with depressed mood
      1. Adjustment Disorder with depressive features
      2. Dysthymia
      3. Bipolar Disorder
    2. Eating Disorder
      1. Anorexia Nervosa
      2. Bulimia Nervosa
    3. Chemical Dependency
      1. Alcohol Abuse
      2. Barbiturate Abuse
      3. Heroin abuse
    4. Miscellaneous psychiatric illness
      1. Anxiety Disorder
      2. Schizophrenia
  9. Causes: Miscellaneous
    1. Chronic Obstructive Pulmonary Disease
    2. Hepatic failure
    3. Systemic Lupus Erythematosus
  10. References
    1. Ferris (1995) Depression Primary Care, PGM, p.36-44
    2. Citrome (1994) Postgrad Med 95(1): 137-45 [PubMed]
    3. Kuzel (1996) Postgrad Med 99(5): 179-95 [PubMed]
    4. Richardson (2005) Curr Probl Pediatr Adolesc Health Care 35(1): 9 [PubMed]

Major Depressive Disorder (C1269683)

Definition (MSH) Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
Definition (PSY) Affective disorder marked by dysphoric mood, inactivity, lack of interest, insomnia, feelings of worthlessness, diminished ability to think, and thoughts of suicide. Use DEPRESSION (EMOTION) for nonclinical depression.
Definition (CSP) one or more periods of depression in the absence of history of manic or hypomanic episodes; chronic type lasts 2 or more years; melancholic type is more severe, has vegetative signs, and responds well to somatic therapy.
Concepts Mental or Behavioral Dysfunction (T048)
MSH D003865
ICD10 F32.9
SnomedCT 370143000, 35489007
English Disorder, Major Depressive, Disorders, Major Depressive, Major Depressive Disorders, MDD, MAJOR DEPRESSIVE DISORDER, DEPRESSIVE DIS MAJOR, MAJOR DEPRESSIVE DIS, Major depressive disorder NOS, Major depressive illness, Major depression NOS, Depressive Disorder, Major [Disease/Finding], major depressive illness, major depressive disorder, major depression, Major depressive disorder (diagnosis), Major depression, Major depressive disorder (disorder), Major depressive disorder, Major depression, NOS, Major depressive disorder, NOS, Depressive Disorder, Major, Depressive Disorders, Major, Major Depressive Disorder, Major Depression
Dutch depressieve ziekte, depressieve stoornis NAO, major depression, Depressieve stoornis, ernstige, Ernstige depressieve stoornis, Involutiepsychose, Melancholie, involutionele, Parafrenie, involutionele, Psychose, involutionele, Involutiedepressie, Involutionele depressie
French Syndrome dépressif majeur SAI, Épisode dépressif majeur, Dépression grave, Grave dépression, Dépression majeure, Trouble dépressif majeur
German Major Depression NNB, schwere depressive Krankheit, Endogene Depression, Involutionsdepression, Melancholie, Involutions-, Paraphrenie, Involutions-, Psychose, Involutions-, Depressive Störung, majore, Majore depressive Störung
Italian Depressione maggiore NAS, Malattia depressiva maggiore, Depressione maggiore, Disturbo depressivo maggiore
Portuguese Doença depressiva major, Perturbação depressiva major NE, Depressão grave, Transtorno Depressivo Maior
Spanish Trastorno depresivo mayor NEOM, Enfermedad depresiva mayor, depresión mayor, trastorno depresivo mayor (trastorno), trastorno depresivo mayor, Depresión mayor, Trastorno Depresivo Mayor
Japanese 大うつ病NOS, オオウツビョウ, ダイウツビョウ, ダイウツビョウNOS, うつ病-退行期, 大うつ病性障害, 大鬱病, うつ病-更年期, 大うつ病, 初老期うつ病, 更年期うつ病, 更年期鬱病, 精神病-更年期, 退行期うつ病, 退行期パラフレニー, 退行期メランコリア, 退行期精神病, 鬱病-更年期, パラフレニー-退行期, 更年期うつ状態, 更年期メランコリー, 更年期精神病, 更年期鬱状態, 精神病-退行期, 退行期鬱病
Swedish Involutionsdepression
Czech psychóza involuční, deprese involuční, depresivní porucha unipolární, melancholie involuční, parafrenie involuční, Velké depresivní onemocnění, Velká deprese, Velká depresivní porucha NOS
Finnish Laaja-alainen masentuneisuushäiriö
Polish Wielkie zaburzenie depresyjne, Zaburzenie depresyjne wielkie, Ciężkie zaburzenie depresyjne, Depresja wielka, Parafrenia inwolucyjna, Depresja głęboka, Epizod depresji dużej, Depresja inwolucyjna
Hungarian Major depressiós betegség, Major depressio, Major depressiós zavar k.m.n.
Norwegian Depresjon, alvorlig, Markert depresjon, Depresjon, markert, Alvorlig depresjon, Markant depressiv forstyrrelse
Derived from the NIH UMLS (Unified Medical Language System)

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