Mental Health Book

Opioid

Tobacco Use Disorders

Amphetamine Use Disorders

Background Information

Alcohol Use Disorders

Marijuana

GHB

Hallucinogen Use Disorders

Inhalants

Compulsive Behavior

Sedative Abuse

Dermatology Chapter related topics

Examination Chapter related topics

Sports Medicine Chapter related topics

Ophthalmology Chapter related topics

Pathology and Laboratory Medicine Chapter related topics

Neurology Chapter related topics

Obstetrics Chapter related topics

Pediatrics Chapter related topics

Pharmacology Chapter related topics

//fpnotebook.com/

GHB Withdrawal

Aka: GHB Withdrawal, Gamma Hydroxybutyrate Withdrawal
  1. See Also
    1. Gamma Hydroxybutyrate
    2. Chemical Dependency
    3. Drug Withdrawal
  2. Pathophysiology
    1. GHB Dependence is rare due to rapid elimination
    2. GHB Dependence may occur with excessive use
      1. Chronic use (common in bodybuilders)
      2. Frequent dosing (evert 1-3 hours around the clock)
  3. Symptoms: Withdrawal
    1. Early symptoms
      1. Insomnia
      2. Tremor
      3. Anxiety
      4. Confusion
      5. Nausea and Vomiting
    2. Later symptoms
      1. Agitation
      2. Vivid Hallucinations
      3. Combative behavior
      4. Disorientation
      5. Seizures
    3. Associated Symptoms: Autonomic Instability
      1. Tachycardia
      2. Hypertension
      3. Tremor
      4. Diaphoresis
  4. Differential Diagnosis
    1. Other Sedative-Hypnotic Use
    2. Alcohol Withdrawal
    3. SympathomimeticIntoxication
    4. Serotonin Syndrome
    5. Neuroleptic Malignant Syndrome
    6. Thiamine deficiency
    7. Thyrotoxicosis
    8. Pheochromocytoma
    9. Steroid Psychosis
  5. Labs
    1. See Gamma Hydroxybutyrate
  6. Management
    1. Agitation may require initial restraints (Agitated Delirium)
      1. Four point Physical Restraints may be needed initially
      2. Treat with sedation agents below
      3. See Chemical Restraints
    2. Sedation
      1. Benzodiazepine
      2. Barbiturate
    3. Other symptomatic management
      1. Consider other GABA-B Agonists (e.g. Baclofen)
  7. References
    1. Masom and Tomaszewski (2018) Crit Dec Emerg Med 32(11): 23
    2. Dyer (2001) Ann Emerg Med 37(2):147-52 [PubMed]

You are currently viewing the original 'fpnotebook.com\legacy' version of this website. Internet Explorer 8.0 and older will automatically be redirected to this legacy version.

If you are using a modern web browser, you may instead navigate to the newer desktop version of fpnotebook. Another, mobile version is also available which should function on both newer and older web browsers.

Please Contact Me as you run across problems with any of these versions on the website.

Navigation Tree