//fpnotebook.com/
Pemoline
Aka: Pemoline, Cylert- See Also
- Attention Deficit Disorder in Children
- School Problem Evaluation
- Attention Deficit Disorder in Adults
- ADHD Diagnosis
- ADHD Differential Diagnosis
- ADHD Comorbid Conditions
- ADHD Non-Pharmacologic Management
- ADHD Medications
- Dextroamphetamine (Dexedrine, Dextrostat, Adderall) or Lisdexamfetamine (Vyvanse)
- Methylphenidate (Ritalin, Methylin, Concerta)
- Atomoxetine (Strattera)
- Indications
- Attention Deficit Hyperactivity Disorder (ADHD)
- No longer available in United States
- Not recommended for use due to hepatotoxicty
- Attention Deficit Hyperactivity Disorder (ADHD)
- Pharmacokinetics
- Onset: 2 hours
- Duration: 6 to 10 hours
- Steady state reached in 2 to 3 days
- Titrate dose every 3 to 4 weeks
- Dosing
- Range: 0.5 - 2.5 mg/kg/dose (Up to 112.5 mg/day)
- Start: 18.75 mg PO qAM
- Frequency: Once to twice daily
- Monitoring
- Alanine Aminotransferase (ALT)
- Obtain baseline
- Repeat testing every 2 weeks
- Symptom inquiry at every visit
- Anorexia
- Malaise
- Gastrointestinal symptoms
- Dark Urine
- Alanine Aminotransferase (ALT)
- Precautions
- Informed Consent from parents required prior to use
- Adverse Effects
- Hepatic failure of dysfunction
- Choreoathetoid movements
- Other adverse effects similar to Methylphenidate
- References