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Brain Lesion in Children
Aka: Brain Lesion in Children, Brain Tumor in Children, Pediatric Brain Tumor
- See Also
- Brain Tumors of the Posterior Fossa in Children
- Epidemiology
- Peak Incidence: age 3 to 12 years old
- Most common childhood solid neoplasm
- Second only to Leukemia for overall cancer Incidence
- Etiology
- Cranial exposure to radiation
- Meningiomas
- Astrocytomas
- Glioblastoma multiforme
- Genetic Factors
- Family History in 19% of cases overall
- Family History in 30% of Glioblastoma Multiforme
- Associated conditions
- Neurofibromatosis
- Tuberous sclerosis
- Turcot Syndrome
- Li-Fraumeni cancer syndrome
- Von Hippel Lindau
- Causes: Tumor types (under age 20 years)
- Supratentorial (40%)
- Astrocytoma (8-12%)
- Glioblastoma (<5%)
- Craniopharyngioma (5-8%)
- Ependymoma (3-5%)
- Choroid Plexus papilloma (2-3%)
- Pituitary tumor (<1%)
- Pineal tumor (2%)
- Meningioma (<1%)
- Infratentorial (60%)
- Medulloblastoma (18-25%)
- Cerebellar Astrocytoma (15-20%)
- Brain Stem glioma (8-10%)
- Ependymoma (4-6%)
- Schwannoma (<1%)
- Meningioma (<1%)