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Cough Expectorant
Aka: Cough Expectorant, Protussive, Guaifenesin, Robitussin, Humibid, Liquibid, Guaifenex- See Also
- Indications
- Infectious cough (may speed recovery)
- Chronic Bronchitis (clear airway mucus)
- Acute Sinusitis (assists with sinus drainage)
- Guaifenesin
- Short acting agents (e.g. Robitussin)
- Ages 2 to 5 years old: 2.5 ml PO q4h
- Ages 6 to 12 years old: 5 ml PO q4h
- Adults: 10 ml PO q4h
- Long acting agents
- Mucinex (Over-the-counter)
- Humabid LA with new, unproven formulation
- Contains guiacolsulfonate (old expectorant)
- Discontinued agents
- Prior Humibid LA, Liquibid, Guaifenex LA
- Effect
- The only effective expectorant medication per FDA
- Paradoxically also reduces cough in URI
- Due to altered cough receptor sensitivity in URI
- Dicpinigaitis (2003) Chest 124:2178-81 [PubMed]
- Short acting agents (e.g. Robitussin)
- Other Expectorant Preparations (use with caution)
- Nebulized Hypertonic Saline
- Terbutaline (Brethine)
- Beta Adrenergic Agonist (Tachycardia risk)
- Dose (age >12): 2.5 to 5 mg PO q6 hours while awake
- Amiloride (Midamor)
Medication Costs | ||
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guaifenesin (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
GUAIFENESIN 100 MG/5 ML LIQUID | Generic OTC | $0.01 per ml |
GUAIFENESIN 100 MG/5 ML SYRUP | Generic OTC | $0.01 per ml |
GUAIFENESIN 200 MG TABLET | Generic OTC | $0.04 each |
GUAIFENESIN AC COUGH SYRUP | Generic OTC | $0.03 per ml |
GUAIFENESIN DM SYRUP | Generic OTC | $0.01 per ml |
GUAIFENESIN ER 1,200 MG TABLET | Generic OTC | $0.53 each |
GUAIFENESIN ER 600 MG TABLET | Generic OTC | $0.26 each |
GUAIFENESIN-CODEINE SYRUP | Generic OTC | $0.03 per ml |
GUAIFENESIN-PSE ER 600-60 MG | Generic OTC | $0.40 each |
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. |
Guaifenesin (C0018305) |
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Definition (CHV) | An expectorant |
Definition (CHV) | An expectorant |
Definition (CHV) | An expectorant |
Definition (CHV) | An expectorant |
Definition (NCI) | A glyceryl guaiacolate with expectorant effects. Guaifenesin increases respiratory tract mucus secretions, acts as an irritant to gastric vagal receptors and recruits efferent parasympathetic reflexes that cause glandular exocytosis. This agent reduces the viscosity of mucus secretion by reducing adhesiveness and surface tension as well as increasing hydration of mucus. Guaifenesin promotes the efficiency of the mucociliary mechanism important in removing accumulated secretions from the upper and lower airway. |
Definition (MSH) | An expectorant that also has some muscle relaxing action. It is used in many cough preparations. |
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | D006140 |
SnomedCT | 363737009, 87174009, 386184000 |
LNC | LP18968-5, MTHU007063 |
English | Ether, Guaiacol Glyceryl, Glycerol Guaiacolate, Glyceryl Ether, Guaiacol, Guaiacolate, Glycerol, Guaifenesin, Guaiphenesin, Guaiphenezine, 1,2-Propanediol, 3-(2-methoxyphenoxy)-, 3-(o-Methoxyphenoxy)-1,2-propanediol, Glyceryl Guaiacolate, guaifenesin (medication), GUAIFENESIN, Guaifenesin [Chemical/Ingredient], guaiacol glyceryl ether, guaiphenesin, glyceryl guaiacolate, guaifenesin, guaiFENesin, GuaiFENesin, Guaifenesin - chemical, Guaifenesin - chemical (substance), Guaiacol Glyceryl Ether, Glyceryl guaiacolate, Guaianesin, alpha-Glyceryl guaiacol ether, Guaifenesin (product), Guaifenesin (substance) |
Swedish | Guaifenesin |
Czech | guaifenesin, guajakol glycerylether |
Finnish | Guaifenesiini |
Russian | GVAIFENEZIN, GVAIAKOLGLITSERINOVYI EFIR, ГВАЙФЕНЕЗИН, ГВАЯКОЛГЛИЦЕРИНОВЫЙ ЭФИР |
Japanese | グアイフェネシン, グアヤコールグリセリンエーテル, グアイアコールグリセリルエーテル, フストジル |
Polish | Eter glicerynowy gwajakolu, Guaifenezyna |
Spanish | guaifenesina - sustancia química (sustancia), guaifenesina - sustancia química, gliceril guayacolato, guaifenesina (producto), guaifenesina (sustancia), guaifenesina, guayanesina, éter de alfagliceril guayacolato, Guaifenesina, Éter Guayacol Glicerilo |
French | Éther glycérique du gaïacol, Éther glycérogaïacolique, Éther monoglycérique du gaïacol, Gaïacolate de glycérol, Gaïacolate de glycéryle, Glycéryl gaïacolate, Glycérylgaïacol, Glycéryl guaïacolate, Guaïanésine, Guaïfénésine, Guaïphénésine |
German | Guaifenesin, Guaiphenesin, Guajakolglycerinether |
Italian | Guaifenesina |
Portuguese | Éter Glicerílico do Guaiacol, Guaifenesina |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Guaifenex (C0720747) |
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Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
English | Guaifenex, guaifenex |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Liquibid (C0721382) |
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Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
English | Liquibid, liquibid |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Robitussin (C0723110) |
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Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
English | Robitussin, robitussin |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Humibid (C0729017) |
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Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | D006140 |
English | humibid, Humibid |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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