Pulmonology Book


Multidrug Resistance Score

Aka: Multidrug Resistance Score, MDR Score, Healthcare Associated Multidrug Resistance Risk in Pneumonia
  1. See Also
    1. Pneumonia
    2. Pneumonia Management
    3. Drug Resistance in Pneumonia Score (DRIP Score)
    4. Healthcare Associated Pneumonia (HCAP)
  2. Indications
    1. Identify Pneumonia patients at risk for multi-drug resistance (esp. Healthcare Associated Pneumonia or HCAP)
  3. Criteria
    1. Any antibiotics in the last 90 days
    2. Hospitalization for >2 days in the last 90 days
    3. Poor functional status
      1. Significant debility
      2. Incontinence
      3. Inability to perform Activities of Daily Living (ADLs)
    4. Immunosuppression
      1. Absolute Neutrophil Count <1000
      2. Asplenia
      3. Hematologic Malignancy
      4. Congenital Immunodeficiency
      5. HIV Infection
      6. Prednisone equivalent >10 mg/day for 14 days or more
      7. Other immunosuppressive Medication
  4. Interpretation
    1. Score 0-1: Low risk for multi-drug resistant lung infections
    2. Score >=2: High risk for multi-drug resistance lung infections
  5. References
    1. Maruyama (2013) Clin Infect Dis 57(10): 1373-83 +PMID: 23999080 [PubMed]
    2. Park (2013) Int J Tuberc Lung Dis 17(5): 704-9 +PMID: 23575340 [PubMed]

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