Infectious Disease Book

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Td Vaccine

Aka: Td Vaccine, Tetanus Diphtheria Vaccine, Tetanus Toxoid
  1. Indications
    1. See Tetanus Prophylaxis
    2. Largely replaced in U.S. by Tetanus Vaccines that contain diptheria and Pertussis
    3. Use DTaP Vaccine instead for children under age 7 years
    4. Use Tdap Vaccine instead for teens over age 11 and adults under age 65 years old
  2. Dose
    1. Adult 0.5 ml IM
    2. Interval
      1. Low risk patients: every 8-10 years
      2. Risk of repeat exposure: every 5 years
    3. Warming Vaccine in hands does not reduce pain
      1. Maiden (2003) Med J Aust 178:433-6 [PubMed]
  3. Safety
    1. Safe in HIV
      1. See Immunization in HIV
    2. Safe in Pregnancy (wait until after first trimester)
      1. See Immunzation in Pregnancy
    3. Anaphylaxis rare
    4. No death has been associated with Vaccine since 1978
    5. References
      1. (1996) MMWR Morb Mortal Wkly Rep 45(No. RR-12):1-35 [PubMed]

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