Infectious Disease Book

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qSOFA Score

Aka: qSOFA Score, Quick Sequential Organ Failure Assessment
  1. See Also
    1. Sequential Organ Failure Assessment Score (SOFA Score)
    2. Sepsis in Adults
    3. SIRS Score
  2. Indications
    1. Sepsis and its prognosis (alternative to SIRS Criteria)
  3. Criteria: One point assigned for each of 3 positive criteria
    1. Respiratory Rate >22 breaths/min
    2. Systolic Blood Pressure <100 mmHg
    3. Altered Mental Status
  4. Interpretation
    1. qSOFA Score 2 consistent wth Sepsis (if infectious source)
    2. qSOFA Score <2 is associated with a mortality of 3%, compared with 24% mortality for score of 2-3
    3. Prediction of in-hospital mortality
      1. Test Sensitivity: 70%
      2. Test Specificity: 80%
  5. Precautions
    1. qSOFA Score alone has inadequate Test Sensitivity in Sepsis
      1. Positive qSOFA Score should prompt aggressive Resuscitation for Sepsis
      2. Negative qSOFA Score and a suspicion for Sepsis, should prompt complete SOFA Score calculation
      3. Maitra (2018) Clin Microbiol Infect 24(11): 1123-9
      4. Tusgul (2017) Scand J Trauma Resusc Emerg Mefd 25(1):108 [PubMed]
  6. References
    1. Churpek (2017) Am J Respir Crit Care Med 195(7):906-11 +PMID: 27649072 [PubMed]
    2. Freund (2017) JAMA 317(3): 301-8 [PubMed]
    3. Moskowitz (2017) Crit Care Med 45(11): 1813-9 [PubMed]

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