Hematology and Oncology Book


Physiologic Anemia of Infancy

Aka: Physiologic Anemia of Infancy
  1. See Also
    1. Pediatric Anemia
  2. Definition
    1. Normal Hemoglobin decrease in young infants
  3. Physiology
    1. Hemoglobin drops to low point at age 6 to 8 weeks
    2. Erythropoietin nadir drops Hemoglobin
      1. Term Infants: Hemoglobin drops to 9-11 g/dl
      2. Preterm Infants: Hemoglobin drops to 7-9 g/dl
  4. Differential Diagnosis
    1. See Normocytic Anemia
    2. Human Parvovirus B19 (Fifth Disease)
    3. Hemolytic Anemia (e.g. G6PD Deficiency)
  5. Management
    1. No work-up or treatment unless Hemoglobin lower than expected
  6. References
    1. Oblender in Daechner (1991) Pediatrics, p. 283
    2. Irwin (2001) Am Fam Physician 64(8):1379-86 [PubMed]

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