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Total Iron Binding Capacity
Aka: Total Iron Binding Capacity, TIBC
- Measurement
- Transferrin carries 2 iron atoms per molecule
- Transferrin is normally 30% bound to iron
- TIBC reflects a measurement of serum Transferrin
- Measured by saturating all available binding sites
- Interpretation: Normal
- Range: 250-460 ug/dl
- Interpretation: Increased TIBC
- Iron Deficiency Anemia
- Third trimester Pregnancy
- Polycythemia Vera
- Interpretation: Decreased TIBC
- Anemia of Chronic Disease
- Hemolytic Anemia
- Hemochromatosis
- Chronic Liver Disease or Cirrhosis
- Hypoproteinemia
- Malnutrition
- Pernicious Anemia
- Sickle Cell Anemia