Hematology and Oncology Book



Total Iron Binding Capacity

Aka: Total Iron Binding Capacity, TIBC
  1. Measurement
    1. Transferrin carries 2 iron atoms per molecule
    2. Transferrin is normally 30% bound to iron
    3. TIBC reflects a measurement of serum Transferrin
      1. Measured by saturating all available binding sites
  2. Interpretation: Normal
    1. Range: 250-460 ug/dl
  3. Interpretation: Increased TIBC
    1. Iron Deficiency Anemia
    2. Third trimester Pregnancy
    3. Polycythemia Vera
  4. Interpretation: Decreased TIBC
    1. Anemia of Chronic Disease
    2. Hemolytic Anemia
    3. Hemochromatosis
    4. Chronic Liver Disease or Cirrhosis
    5. Hypoproteinemia
    6. Malnutrition
    7. Pernicious Anemia
    8. Sickle Cell Anemia

Serum Total Iron-Binding Capacity result (C0036835)

Concepts Laboratory or Test Result (T034)
English TIBC, TIBC - Tot iron bind capacity, TIBC - Total iron binding capacity, Total iron binding capacity, tibc, total iron binding capacity (TIBC) test, Serum Total Iron-Binding Capacity result
Dutch TIBC
French CTFF
German TIBC
Italian Capacità totale di legame per il ferro
Portuguese Capacidade total de fixação de ferro
Spanish CTFH
Japanese TIBC, TIBC
Czech TIBC
Hungarian TIBC
Derived from the NIH UMLS (Unified Medical Language System)

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