Hematology and Oncology Book



Serum Iron

Aka: Serum Iron
  1. Measurement
    1. Measures Transferrin-associated ferric ion
    2. Related measures
      1. Total Iron Binding Capacity
      2. Percent Transferrin Saturation
  2. Interpretation: Normal
    1. Range: 50 - 175 ug/dl
  3. Interpretation: Elevated Serum Iron
    1. Hemochromatosis
    2. Hemolysis
    3. Hemolytic Anemia
    4. Hemosiderosis
    5. Hepatic necrosis
    6. Hepatitis
    7. Ineffective Erythropoiesis
      1. Vitamin B12 Deficiency
    8. Iron Poisoning or Iron Overdose
    9. Lead Toxicity or Lead Poisoning
    10. Transient increases
      1. Diurnal variation (increases in evening)
      2. Recent meat ingestion or iron intake
  4. Interpretation: Decreased Serum Iron
    1. Chronic Gastrointestinal Blood loss
    2. Heavy Menstrual Bleeding
    3. Inadequate iron absorption
    4. Insufficient Dietary Iron
    5. Iron Deficiency Anemia
    6. Malabsorption
    7. Nephrotic Syndrome
    8. Third trimester of pregnancy

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