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First Generation Progestin
Aka: First Generation Progestin, Norethindrone, Norethynodrel- See Also
- Class
- 19 Nor-TestosteroneProgestin: Estrane
- Norethindrone
- Relative Progestational Activity: 1.0
- Estrogenic Activity: 1.0
- Androgenic Activity: 1.0
- Endometrial Activity: 1.0
- Anti-Estrogen: Active
- Preparations
- Ethinyl Estradiol
- Brevicon or Modicon (0.5/35)
- Ovcon (0.4/35, 1/50)
- Norinyl or Ortho-Novum 1/35
- Ortho-Novum 10/11 Biphasic (0.5-1.0/35)
- Ortho-Novum 7/7/7 Triphasic (0.5-0.75-1.0/35)
- Tri-Norinyl Triphasic (0.5-1.0-0.5/35)
- Mestranol (50 mcg is equivalent to 35 mcg Estradiol, 1 mcg Norethindrone)
- Progestin-only (Mini-Pill)
- Ethinyl Estradiol
- Relative Progestational Activity: 1.0
- Norethynodrel
- Relative Progestational Activity: 0.3
- Estrogenic Activity: 8.3
- Androgenic Activity: 0
- Endometrial Activity: 0
- Anti-Estrogen: Inactive
- Preparations (MestranolEstrogen component)
- Enovid 5 (5/75)
- Enovid E (2.5/100)
- Relative Progestational Activity: 0.3
- References
- Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
- Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
- Dickey (1998) Managing Contraceptive Pill Patients
Medication Costs | ||
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Norethindrone USP (on 6/18/2017 at Walmart.com) | ||
Norethindrone USP | #28 tablets for $9.00 | $0.32 each |
norethindrone (on 5/17/2017 at Medicaid.Gov Pharmacy Drug pricing) | ||
NORETHINDRONE 0.35 MG TABLET | Generic | $0.38 each |
NORETHINDRONE 5 MG TABLET | Generic | $1.31 each |
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. |
Norethindrone (C0028356) |
|
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Definition (NCI) | A synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. Norethindrone binds to the progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. This leads to an alteration in protein synthesis and results in an inhibition of LH release. Consequently, it inhibits ovulation and changes the normal cycle of cervical mucus and endometrium. |
Definition (MSH) | A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. |
Definition (CSP) | synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation; has weak estrogenic and androgenic properties; has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception. |
Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110) |
MSH | D009640 |
SnomedCT | 63758001, 325610003, 326443003, 326332005, 327289001, 326366001, 126102009 |
LNC | LP18482-7, MTHU003100 |
English | Ethinylnortestosterone, Norethisterone, Norpregneninolone, 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-, Norethisterone [combined o/c], Norethisterone [endocrine], Norethisterone [malignancy], Norethisterone [progest o/c], norethindrone, Norethisterone [combined oral contraceptive], Norethisterone [progestogen oral contraceptive], NORETHINDRONE, norethindrone preparations, oral contraceptives norethindrone preparations, norethindrone preparations (medication), Norethindrone [Chemical/Ingredient], norethisterone, Norethisterone [endocrine] (product), Norethisterone [progestogen oral contraceptive] (product), Norethisterone [combined oral contraceptive] (product), Norethisterone [malignancy] (product), Norethindrone preparation, Norethisterone preparation, Norethisterone product, Norethindrone (substance), Norethindrone preparation (product), Norethindrone, Norethindrone preparation (substance), Norethisterone [combined oral contraceptive] (substance), Norethisterone [endocrine] (substance), Norethisterone [malignancy] (substance), Norethisterone [progestogen oral contraceptive] (substance) |
Swedish | Noretindron |
Czech | norethindron |
Finnish | Noretisteroni |
Russian | NORKOLUT, NORETINDRON, ETINILNORTESTOSTERON, NORPREGNENINOLON, NORETISTERON, НОРКОЛУТ, НОРПРЕГНЕНИНОЛОН, НОРЭТИНДРОН, НОРЭТИСТЕРОН, ЭТИНИЛНОРТЕСТОСТЕРОН |
Spanish | noretisterona, preparado con noretindrona (producto), noretisterona (producto), preparado con noretisterona, preparado con noretindrona, noretisterona (uso oncológico) (producto), noretisterona [uso endocrino] (producto), noretisterona (anticonceptivo oral combinado), noretisterona (anticonceptivo oral con progestágeno), noretisterona (uso oncológico), noretisterona [uso endocrino], noretisterona (anticonceptivo oral con progestágeno) (producto), noretisterona (anticonceptivo oral combinado) (producto), noretindrona (sustancia), noretindrona, noretisterona (malignidad) (producto), noretisterona (malignidad), preparado de noretindrona (sustancia), Etinilnortestosterona, Noretindrona, Noretisterona, Norpregneninolona |
Polish | Noretysteron |
Japanese | プリモルトN, エチニルノルテストステロン, 19-ノルエチステロン, ノルルテン, ミクロノル, ノルエチステロン, ノルルチン, ノアルテン, ノルエチンドロン, ノルプレグネニノロン |
French | Noréthistérone |
German | Ethinylnortestosteron, Norethindron, Norethisteron, Norpregneninolon |
Italian | Noretindrone |
Portuguese | Etinilnortestosterona, Noretindrona, Noretisterona, Norpregneninolona |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Norethynodrel (C0028360) |
|
---|---|
Definition (MSH) | A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combination with MESTRANOL. |
Concepts | Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110) |
MSH | D009641 |
SnomedCT | 126107003, 82133001 |
English | Norethynodrel, 19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-, (17alpha)-, oral contraceptives norethynodrel, norethynodrel, norethynodrel (medication), Norethynodrel [Chemical/Ingredient], Norethynodrel preparation, Norethynodrel (substance), Norethynodrel preparation (product), Noretynodrel, Norethynodrel preparation (substance), NORETHYNODREL |
Swedish | Noretynodrel |
Czech | norethynodrel |
Finnish | Noretinodreeli |
Russian | NORETINODREL, НОРЭТИНОДРЕЛ |
Japanese | ノルエチノドレル, ノルエチノドレール, エニドレル, ノルエチニノドレール |
Spanish | noretinodrel (producto), preparado con noretinodrel (producto), preparado con noretinodrel, noretinodrel (sustancia), noretinodrel, preparado de noretinodrel (sustancia), Noretinodrel |
Polish | Noretynodrel |
French | Norétynodrel |
German | Norethynodrel |
Italian | Noretinodrel |
Portuguese | Noretinodrel |
Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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