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Sulfonylurea
Aka: Sulfonylurea, Insulin Secretagogue- See Also
- Oral Hypoglycemic Agents
- Background
- Discovered in 1940's when investigating antibiotics
- Mechanism
- Types
- First Generation Sulfonylurea (Listed for historical purposes only)
- Second Generation Sulfonylurea (e.g. Glipizide, Glyburide)
- Non-Sulfonylurea Insulin Secretagogues (e.g. Meglitinide, Repaglinide)
Sulfonylurea Compounds (C0038766) |
|
|---|---|
| Definition (CSP) | compounds of the type R-SO2-NHCONH-; when R=Ph, these are a group of hypoglycemic agents which enhance insulin secretion by beta cells and insulin sensitivity in target tissue, and so are effective in type II (noninsulin-dependent) diabetes mellitus. |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D013453 |
| SnomedCT | 273950002, 34012005, 372711004, 259552008 |
| LNC | LP18787-9, MTHU005387 |
| English | Compounds, Sulfonylurea, SULFONYLUREA CPDS, Sulfonylurea and its derivs, Sulphonylurea and its derivs, sulfonylureas (medication), sulfonylureas, sulfonylurea compounds, oral hypoglycemics sulfonylureas, Sulfonylurea Compounds, Sulfonylurea Compounds [Chemical/Ingredient], sulphonylureas, sulphonylurea, Sulfonylurea, Sulfonylurea compounds, Sulfonylurea product, Sulphonylurea, Sulphonylurea compounds, Sulphonylurea product, Sulfonylurea and its derivatives, Sulphonylurea and its derivatives, Sulfonylurea (product), Sulfonylurea (substance), Sulfonylurea and its derivatives (substance), sulfonylurea, Sulfonylurea, NOS, Sulfonylurea [dup] (substance), Sulfonylureas |
| Swedish | Sulfonylureaföreningar |
| Czech | sulfonylmočovinové sloučeniny, glibornurid, sulfonylureové deriváty, sulfonylureové sloučeniny |
| Finnish | Sulfonyyliurea |
| Russian | SUL'FONILMOCHEVINY SOEDINENIIA, GLIBORNURID, ГЛИБОРНУРИД, СУЛЬФОНИЛМОЧЕВИНЫ СОЕДИНЕНИЯ |
| Croatian | SULFONILUREJA, SPOJEVI |
| Polish | Sulfonylomocznika związki |
| Portuguese | Compostos de Sulfonilureia |
| Spanish | sulfonilurea (producto), sulfonilurea (sustancia), sulfonilurea y derivados (sustancia), sulfonilurea y derivados, sulfonilurea, Compuestos de Sulfonilurea |
| French | Sulfonylurées |
| German | Sulfonylharnstoffverbindungen |
| Italian | Derivati della solfonilurea |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
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