Dermatology Book

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Topical Fluorouracil

Aka: Topical Fluorouracil
  1. Indications
    1. Keratolytic
  2. Preparations
    1. Cream 5%
    2. Solution 2%
  3. Dosing
    1. Apply bid for 3-4 weeks
  4. Adverse effects
    1. Irritation
    2. Initial significant patient discomfort
    3. Sun sensitizing (Use Sunscreen)
  5. Precautions
    1. Avoid in pregnancy and young children
    2. May cause prolonged hypo-pigmentation
      1. Test first in cosmetically unimportant areas
      2. Hypopigmentation worse in dark skinned patients
    3. Use sparingly on penile shaft
      1. Allow to dry completely
      2. Avoid scrotal contact

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