II. Pathophysiology

  1. Spontaneous endothelial bleeding does not occur until Platelet Count drops to less than 5000

III. Indications: Adults

  1. Platelet Count <100,000
    1. Ocular surgery (no active bleeding)
    2. Neurosurgery (no active bleeding)
  2. Platelet Count <50,000
    1. Major elective surgery (not neurosurgery)
    2. Invasive procedure
    3. Elective diagnostic Lumbar Puncture
  3. Platelet Count <20,000
    1. Fever (over 100.4 F) in an otherwise stable, non-bleeding patient
    2. Central Venous Catheter Placement
  4. Platelet Count <10,000
    1. Stable, non-bleeding patient with hypoproliferative Thrombocytopenia

IV. Indications: Newborns

  1. Platelet Count 30,000 to 50,000
    1. Birth weight <1000 g and first week of life
    2. Cerebral Hemorrhage
    3. Coagulation Disorder
    4. Sepsis
    5. Invasive procedure
    6. Alloimmune neonatal Thrombocytopenia
      1. Directed donation with washed and irradiated products
  2. Platelet Count 20,000 to 30,000
    1. Active bleeding
    2. Lumbar Puncture
  3. Platelet Count <20,000
    1. Stable, non-bleeding patient

V. Labs

  1. Platelet Count
    1. Adults: One apheresis unit (6 pack) increases Platelets 30,000/ul to 40,000/ul per 2.0 m2 BSA
    2. Newborns: 5-10 ml/kg increases Platelets 50-100,000

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Related Studies

Ontology: Platelet Transfusion (C0086818)

Definition (NCI) The infusion of platelets into the bloodstream.
Definition (MSH) The transfer of blood platelets from a donor to a recipient or reinfusion to the donor.
Definition (CSP) transfer of blood platelets from a donor to a recipient or reinfusion to the donor.
Concepts Therapeutic or Preventive Procedure (T061)
MSH D017713
ICD9 99.05
ICD10 13706-03
SnomedCT 151007004, 12719002, 180208003
English Platelet Transfusion, Platelet Transfusions, Transfusion, Platelet, Transfusions, Platelet, Blood Platelet Transfusion, Blood Platelet Transfusions, Platelet Transfusion, Blood, Platelet Transfusions, Blood, Transfusion, Blood Platelet, Transfusions, Blood Platelet, Transfusion of platelets, IV blood transfusion platelets, platelet transfusion, transfusion of platelets (treatment), transfusion of platelets, platelets transfusions, transfusion platelets, blood platelets transfusion, platelets transfusion, platelet transfusions, Blood platelets--Transfusion, Transfusion of thrombocytes, Platelet transfusion, Intravenous blood transfusion of platelets, Intravenous blood transfusion of platelets (procedure), Platelet transfusion (procedure)
Swedish Trombocyttransfusion
Japanese ケッショウバンユケツ, 血小板輸血, 輸血-血小板
Czech trombocyty - transfúze, Transfuze krevních destiček, transfuze trombocytů
Finnish Verihiutaleiden siirto
French Transfusion de plaquettes, Transfusion de thrombocytes, Transfusion plaquettaire
Polish Przetaczanie płytek krwi, Transfuzja płytek krwi, Przetaczanie komórek płytkowych
Hungarian Thrombocyta transzfúzió
Norwegian Trombocyttransfusjon, Blodplatetransfusjon, Trombocytt-transfusjon
Spanish transfusión de plaquetas (procedimiento), transfusión de plaquetas, transfusión de trombocitos, transfusión intravenosa de plaquetas (procedimiento), transfusión intravenosa de plaquetas, transfusión plaquetaria, Transfusión de plaquetas, Transfusión de Plaquetas Sanguíneas, Transfusión de Plaquetas
Portuguese Transfusão de plaquetas, Transfusão de Plaquetas, Transfusão de Plaquetas Sanguíneas
Dutch plaatjestransfusie, Transfusie, trombocyten-, Trombocytentransfusie
German Thrombozytentransfusion, Transfusion, Thrombozyten-, Blutplättchentransfusion
Italian Trasfusione di piastrine

Ontology: Transfusion of plateletpheresis product (C1293887)

Concepts Therapeutic or Preventive Procedure (T061)
SnomedCT 116810007
English Plateletpheresis product administration by intravascular infusion, Transfusion of plateletpheresis product (procedure), Transfusion of plateletpheresis product
Spanish plaquetaféresis mediante infusión intravascular, transfusión de producto de plaquetaféresis (procedimiento), transfusión de producto de plaquetaféresis

Ontology: Apheresis Units, Blood Donor, Platelet (C1961283)

Definition (UMD) Apheresis units designed to automate the separation and collection from and reinfusion of platelets to a healthy blood donor (i.e. perform plateletpheresis). Typically, platelets are collected and the rest of the blood is automatically reinfused; with the use of automated methods, large quantities of platelets can be obtained from a single donor. Blood donor platelet apheresis units usually consist of a disposable pheresis set (i.e., a tubing set that connects the patient to the apheresis unit), pumps (e.g., rotary peristaltic pumps), a centrifugation chamber, bowls, filters, clamps, controls (e.g., centrifuge and pump speed, volume of solution added), alarms, and bubble detectors.
Concepts Medical Device (T074)
English Platelet Apheresis Units, Blood Donor, Apheresis Units, Blood Donor, Platelet

Ontology: Plateletpheresis Units (C3687993)

Concepts Medical Device (T074)
English Plateletpheresis Units