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Ontology:
Loperamide
(C0023992)
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Definition (NCI)
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A synthetic agent chemically related to the opiates with anti-diarrheal properties. Loperamide decreases gastro-intestinal motility by effects on the circular and longitudinal muscles of the intestine. Part of its anti-diarrheal effect may be due to a reduction of gastro-intestinal secretion produced by opioid receptor binding in the intestinal mucosa. (NCI04)
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|
Definition (MSH)
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One of the long-acting synthetic ANTIDIARRHEALS; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.
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| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
| MSH |
D008139
|
| SnomedCT |
116726003, 387040009 |
| LNC |
LP18991-7, MTHU007262 |
| English |
Loperamide, 1-Piperidinebutanamide, 4-(4-chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, loperamide, Loperamide [Chemical/Ingredient], LOPERAMIDE, Loperamide (product), Loperamide (substance) |
| Swedish |
Loperamid
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| Czech |
loperamid
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| Finnish |
Loperamidi
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| Russian |
LOPERAMID, LOPERAMIDGIDROKHLORID, ЛОПЕРАМИД, ЛОПЕРАМИДГИДРОХЛОРИД |
| Japanese |
カグダリン, ロペナ, ロンバニン, ベルテッサ, ロスポリア, ロペミン, ロペラニール, ロペラン, ミロピン, クラレット, ロペカルド, タイペミン, ロペミック, ロペラミド, 塩酸ロペラミド, ロペジャスト, ロペラミド塩酸塩 |
| Polish |
Loperamid
|
| Spanish |
loperamida (producto), loperamida (sustancia), loperamida, Loperamida |
| French |
Lopéramide
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| German |
Loperamid
|
| Italian |
Loperamide
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| Portuguese |
Loperamida
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Ontology:
Imodium
(C0591635)
| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
| MSH |
D008139
|
| English |
imodium, Imodium |
