II. Pathophysiology

  1. Terminal ileum fails to reabsorb bile acids
  2. Results in Secretory Diarrhea (Chronic Watery Diarrhea)

III. Associated Conditions

  1. Irritable Bowel Syndrome
    1. One third malabsorb bile acids
  2. Microscopic Colitis
    1. One third malabsorb bile acids
  3. Crohn Disease Diarrhea
  4. Post-CholecystectomyDiarrhea

IV. Labs: Experimental

  1. Serum 7a-hydroxy-4-cholesten-3-one
    1. Increased in Bile Acid Malabsorption
  2. Fibroblast growth factor 19
    1. Decreased in Bile Acid Malabsorption

V. Imaging: Not available in U.S.

  1. Selenium homocholic acid taurocholate scanning (SeHCAT)
    1. Radionuclide tracer used in whole body gamma imaging (Not FDA approved in U.S.)

VI. Management

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Ontology: Bile acid malabsorption (C2747802)

Concepts Disease or Syndrome (T047)
English Bile acid malabsorption
Spanish Mala absorción de ácidos biliares
Portuguese Malabsorção de ácido biliar
Dutch galzuur malabsorptie
Italian Malassorbimento di acidi biliari
Czech Malabsorpce žlučových kyselin
French Malabsorption des acides biliaires
Japanese 胆汁酸吸収不良, タンジュウサンキュウシュウフリョウ
Hungarian Epesav malabsorptio
German Gallensaeure-Fehlabsorption