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Oxcarbazepine

Aka: Oxcarbazepine, Trileptal
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  1. Indications
    1. Simple Partial Seizures
    2. Complex Partial Seizures
    3. Generalized Tonic Clonic Seizures
    4. Trigeminal Neuralgia
    5. Mania
  2. Adverse Effects: Dose related
    1. Nausea or Vomiting
    2. Dizziness
    3. Ataxia
    4. Diplopia
    5. Sedation
    6. Lethargy
    7. Hyponatremia
    8. Tremor
  3. Adverse Effects: Other
    1. Hyponatremia
    2. Cardiac arrhythmia
  4. Dosing: Adults (includes elderly)
    1. Initial: 300 mg PO bid
    2. Increase by 600 mg/day weekly
    3. Target dose: 600 mg PO bid
Medication Costs
OXcarbazepine (on 2/9/2012 at DrugStore.com)
OXcarbazepine 300mg/5ml Suspension 250ml Bottle #1 for $147.99 ($147.99/unit)
OXcarbazepine 150mg Tablets #30 for $39.99 ($1.33/unit)
OXcarbazepine 300mg Tablets #60 for $131.00 ($2.18/unit)
OXcarbazepine 600mg Tablets #60 for $259.98 ($4.33/unit)
Trileptal (on 2/9/2012 at DrugStore.com)
Trileptal 300mg Tablets #60 for $245.99 ($4.10/unit)
Trileptal 150mg Tablets #60 for $134.99 ($2.25/unit)
Trileptal 600mg Tablets #60 for $450.01 ($7.50/unit)
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

oxcarbazepine (C0069751)

Definition (NCI) A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses.
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C036006
SnomedCT 323042005, 116511002, 387025007
English oxcarbazepine, 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, oxcarbazepine (medication), OXCARBAZEPINE, oxcarbazepine [Chemical/Ingredient], oxcarbazepine substance, OXcarbazepine, Oxcarbazepine (product), Oxcarbazepine (substance), Oxcarbazepine
Spanish Oxcarbazepine, oxcarbacepina, oxcarbazepina (producto), oxcarbazepina (sustancia), oxcarbazepina
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Trileptal (C0876196)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C036006
English trileptal, Novartis brand of oxcarbazepine, Trileptal
Japanese オクスカルバゼピン
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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