II. Indications
III. Mechanism
- See Antihistamine
- H1 Receptor Antagonist
- Carbinoxamine Maleate is an Ethanolamine First Generation Antihistamine with high Anticholinergic activity
IV. Precautions
- Although FDA approved for children, FDA does not recommend routine Antihistamine use age <4 years
- Deaths have occurred in younger children related to Anticholinergic Toxicity
V. Dosing: Regular Release Formulation
- Adult: 4 to 8 mg orally three to four times daily
- Child age 2 to 3 years: 2 mg orally three to four times daily
- Child age 3 to 6 years: 2 to 4 mg orally three to four times daily
- Child age 2 to 3 years: 4 to 6 mg orally three to four times daily
VI. Adverse Effects
- See Antihistamine
- See Anticholinergic Toxicity
- Sedation
VII. Safety
- Pregnancy category C
- Avoid in Lactation
VIII. Resources
- Carbinoxamine (DailyMed)
IX. References
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 146-7
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
Images: Related links to external sites (from Bing)
Related Studies
| carbinoxamine (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| CARBINOXAMINE MALEATE 4 MG TAB | Generic | $0.34 each |
| ryvent (on 9/9/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| RYVENT 6 MG TABLET | $6.79 each | |