II. Indications
- Multi-drug Tuberculosis Treatment regimen
III. Background
- Only 10% of drug penetrates Tb infected cells
IV. Dosing
- Adult: 1 gram (15 mg/kg) IM qd
- Pediatric: 20-40 mg/kg/day
V. Adverse Effects
-
Cranial Nerve 8 and Vestibular toxicity
- Vertigo
- Decreased Hearing acuity or Deafness
- Renal damage