Sporotrichosis

Aka: Sporotrichosis, Sporothrix schenckii

II. Pathophysiology

  1. Saprophytic, Dimorphic fungus
  2. Prototypal example of Nodular Lymphangitis

III. Exposure risks

  1. Soil or plant debris
  2. Thorns
  3. Sphagnum moss
  4. Timber
  5. Animal Bites or scratches

IV. Signs

  1. Primary lesion after 1-12 week incubation
    1. Nodular lesion develops at site of inoculation
  2. Secondary lesions
    1. Erythematous Papules, Nodules develop up lymph chain
    2. Lesions ulcerate and drain clear serous fluid
  3. Other findings
    1. Rarely fever or regional adenopathy occur

V. Differential Diagnosis

  1. See Nodular Lymphangitis

VI. Labs

  1. Routine fluid culture negative
  2. Culture of biopsied tissue shows saprophytic fungi

VII. Management

  1. Apply warm compresses for 40 to 60 minutes per day
  2. Antifungal for 2 months after lesion resolution
    1. Itraconazole 200 mg PO qd (preferred)
    2. Terbinafine (Lamisil) 250 mg PO bid
    3. SSKI 5 drops PO tid (titrated to 40-50 drops tid)

VIII. References

  1. Kauffman (1995) Clin Infect Dis 21:981-5 [PubMed]
  2. Tobin (2001) Am Fam Physician 63(2):326-32 [PubMed]

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Related Studies

Ontology: Sporotrichosis (C0038034)

Definition (MSH) The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues. It is caused by inhalation of contaminated dust or by infection of a wound.
Concepts Disease or Syndrome (T047)
MSH D013174
ICD9 117.1
ICD10 B42 , B42.9
SnomedCT 266218008, 154408001, 187488001, 187078008, 42094007
English Sporotrichoses, Sporotrichosis NOS, Sporotrichosis, unspecified, [X]Sporotrichosis, unspecified, sporotrichosis, sporotrichosis (diagnosis), Sporothric schenckii infection, Sporotrichosis [Disease/Finding], schenck disease, Sporothrix schenckii infection, [X]Sporotrichosis, unspecified (disorder), Sporotrichosis NOS (disorder), Infection by Sporothrix schenkii, Sporotrichosis (disorder), Schenck, Beurmann, De, De Beurmann, Sporotrichosis
Dutch Sporothrix schenckii-infectie, sporotrichose NAO, Sporotrichose, niet gespecificeerd, sporotrichose, Sporotrichose, Sporotrichosis
French Sporotrichose SAI, Infection à Sporothrix schenckii, Infection à Sporothric schenckii, Sporotrichose, Maladie de Bevermann-Gougerot, Maladie de De Beurmann et Gougerot, Maladie de Schenk
German Sporothrix schenckii-Infektion, Sporotrichose NNB, Sporotrichose, nicht naeher bezeichnet, Sporotrichose
Italian Infezione da Sporothrix schenckii, Sporotricosi NAS, Sporotricosi
Portuguese Esporotricose NE, Infecção por Sporothrix schenckii, Esporotricose
Spanish Infección por Sporothrix schenckii, Esporotricosis NEOM, [X]esporotricosis, no especificada (trastorno), [X]esporotricosis, no especificada, esporotricosis, SAI (trastorno), esporotricosis, SAI, esporotricosis (trastorno), esporotricosis, infección por Sporothrix schenkii, Esporotricosis
Japanese スポロトリコーシス, スポロトリコーシスＮＯＳ, ｽﾎﾟﾛﾄﾘｺｰｼｽ, ｽﾎﾟﾛﾄﾘｺｰｼｽNOS, ｽﾎﾟﾛﾄﾘｯｸｽｼｪﾝｷｲｶﾝｾﾝ, スポロトリックス・シェンキイ感染
Swedish Sporotrikos
Czech sporotrichóza, Sporotrichóza, Infekce Sporothric schenckii, Sporotrichóza NOS, Infekce Sporothrix schenckii
Finnish Sporotrikoosi
Russian SPOROTRIKHOZ, СПОРОТРИХОЗ
Korean 스포로트리쿰증, 상세불명의 스포로트리쿰증
Polish Grzybica sporotrychowa, Sporotrychoza, Choroba Schencka
Hungarian sporotrichosis, sporotrichosis k.m.n., Sporothrix schenckii infectio, Sporothrix schenckii fertőzés
Norwegian Sporotrikose
Derived from the NIH UMLS (Unified Medical Language System)

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