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Clonazepam
Aka: Clonazepam, Klonopin- See Also
- Class
- Long acting Benzodiazepine
- Indications
- Dosing
- Initial: 0.25 to 0.5 mg PO tid
- Titrate: Increase by 0.5 to 1 mg increments q3 days
- Maximum Daily Dose: 20 mg
- Pharmacokinetics
- Half Life: 24-48 hours
- Rapidly and completely absorbed PO
- Equivalent Dosing (for Benzodiazepine Withdrawal)
- Valium = Clonazepam Dose x2.5
- Phenobarbital = Clonazepam Dose x7.5
- Adverse Effects
- Sedation
- Weight gain
- Impaired academic performance
- Social anxiety with School Refusal in children
- Worsening of attention in children with ADHD
- Hypersalivation
| Medication Costs | ||
|---|---|---|
| ClonazePAM (on 2/9/2012 at DrugStore.com) | ||
| ClonazePAM 2mg Tablets | #30 for $12.99 | ($0.43/unit) |
| ClonazePAM 0.5mg Tablets | #30 for $13.99 | ($0.47/unit) |
| ClonazePAM 1mg Tablets | #30 for $11.99 | ($0.40/unit) |
| ClonazePAM ODT (on 2/9/2012 at DrugStore.com) | ||
| ClonazePAM ODT 0.125mg Dispersible Tablet | #60 for $69.99 | ($1.17/unit) |
| ClonazePAM ODT 0.25mg Dispersible Tablet | #60 for $76.99 | ($1.28/unit) |
| ClonazePAM ODT 0.5mg Dispersible Tablet | #60 for $74.99 | ($1.25/unit) |
| ClonazePAM ODT 1mg Dispersible Tablet | #60 for $80.99 | ($1.35/unit) |
| ClonazePAM ODT 2mg Dispersible Tablet | #60 for $105.99 | ($1.77/unit) |
| KlonoPIN (on 2/9/2012 at DrugStore.com) | ||
| KlonoPIN 1mg "on Manufacturer Backorder, Estimated Release Date Of Late July" | #30 for $65.99 | ($2.20/unit) |
| KlonoPIN 0.5mg Tablets | #30 for $60.99 | ($2.03/unit) |
| KlonoPIN 2mg Tablets | #30 for $89.99 | ($3.00/unit) |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
Clonazepam (C0009011) |
|
|---|---|
| Definition (CHV) | a kind of anti-anxiety drug also used to treat sleep disorders |
| Definition (MSH) | An anticonvulsant used for several types of seizures, including myotonic or atonic seizures, photosensitive epilepsy, and absence seizures, although tolerance may develop. It is seldom effective in generalized tonic-clonic or partial seizures. The mechanism of action appears to involve the enhancement of GAMMA-AMINOBUTYRIC ACID receptor responses. |
| Definition (NCI) | A synthetic benzodiazepine derivative used for myotonic or atonic seizures, absence seizures, and photosensitive epilepsy, anticonvulsant Clonazepam appears to enhance gamma-aminobutyric acid receptor responses, although its mechanism of action is not clearly understood. It is seldom effective in generalized tonic-clonic or partial seizures. (NCI04) |
| Definition (CSP) | 5-(o-chlorophenyl)-1,3-dihydro -7-nitro-2H-1,4-benzodiazepin-2-one; anticonvulsant used against epileptic seizures and tardive dyskinesia. |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | D002998 |
| SnomedCT | 323076001, 322892002, 387383007, 69708003 |
| English | Clonazepam, 2H-1,4-Benzodiazepin-2-one, 5-(2-chlorophenyl)-1,3-dihydro-7-nitro-, Clonazepam [epilepsy control], Clonazepam [status epilepsy], clonazepam, Clonazepam [status epilepsy] (product), Clonazepam [epilepsy control] (product), clonazepam (medication), CLONAZEPAM, Clonazepam [Chemical/Ingredient], clonazePAM, Clonazepam (product), Clonazepam (substance), Clonazepam [epilepsy control] (substance), Clonazepam [status epilepsy] (substance) |
| Swedish | Klonazepam |
| Czech | klonazepam |
| Finnish | Klonatsepaami |
| Russian | ANTELEPSIN, KLONAZEPAM, АНТЭЛЕПСИН, КЛОНАЗЕПАМ |
| Spanish | clonazepam [estado epiléptico], clonazepam [estado epiléptico] (producto), clonazepam [antiepiléptico] (producto), clonazepam [antiepiléptico], clonazepam (producto), clonacepam (producto), clonacepam, clonacepam (sustancia), clonazepam (sustancia), clonazepam, Clonazepam |
| Japanese | クロナゼパム, リボトリール |
| Polish | Klonazepam |
| French | Clonazépam |
| German | Clonazepam |
| Italian | Clonazepam |
| Portuguese | Clonazepam |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Klonopin (C0699315) |
|
|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| English | Klonopin, klonopin, klonopins, KlonoPIN |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |