II. Indications
III. Mechanism
- Synthetic Anticholinergic, carboxylic acid derivative
- Selective Acetylcholine blockade of Muscarinic Receptors on Smooth Muscles
- Results in Smooth Muscle relaxation and antispasmodic activity
- Effects
- Relaxes gastrointestinal Smooth Muscle and decreases spasm
- Inhibits gastrointestinal motility
- Decreases gastric acid secretion
- Decreases Saliva and brochial secretions
IV. Dosing: Adult
- Start 20 mg orally four times daily as needed
- Increase to 40 mg orally four times daily as needed
- Typical effective dose (160 mg/day)
V. Dosing: Child
- Not FDA approved
VI. Adverse Effects
VII. Safety
- Pregnancy Category B
- Unknown safety in Lactation
VIII. Resources
IX. References
- (2020) Med Lett Drugs Ther 62(1594): 41-58
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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