Infectious Disease Book

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Famciclovir

Aka: Famciclovir, Famvir
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  1. Indications
    1. Herpes Zoster (Shingles)
    2. Recurrent Genital Herpes
    3. Recurrent HSV in immunocompromised patients
  2. Dosing
    1. Herpes Zoster (Shingles)
      1. Adult: 500 mg PO q8 hours for 7 days
    2. Genital Herpes
      1. Initial: 250 mg PO tid for 7-10 days
      2. Recurrent immunocompetent: 125 mg PO bid for 5 days
      3. Recurrent in HIV: 500 mg PO bid for 7 days
      4. Prophylaxis: 250 mg PO bid for up to 12 months
  3. Pharmacokinetics
    1. Adjust dose for Creatinine Clearance <60 ml/min
  4. Adverse Effects
    1. Headache
    2. Nausea or Vomiting
    3. Fatigue
    4. Paresthesias
    5. Pruritus
Medication Costs
Famciclovir (on 2/9/2012 at DrugStore.com)
Famciclovir 125mg Tablets #30 for $159.99 ($5.33/unit)
Famciclovir 250mg Tablets #30 for $169.99 ($5.67/unit)
Famciclovir 500mg Tablets #30 for $326.00 ($10.87/unit)
Famvir (on 2/9/2012 at DrugStore.com)
Famvir 125mg Tablets #30 for $201.00 ($6.70/unit)
Famvir 250mg Tablets #30 for $216.99 ($7.23/unit)
Famvir 500mg Tablets #30 for $450.01 ($15.00/unit)
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

famciclovir (C0209227)

Definition (NCI) A diacetyl 6-deoxy prodrug analog of the antiviral agent penciclovir. Orally administered, famciclovir in vivo is converted to penciclovir triphosphate, which is active against the Herpes viruses, including herpes simplex 1 and 2 and varicella-zoster. This agent inhibits the replication of viral DNA by interfering competitively with DNA polymerase. (NCI04)
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C060590
SnomedCT 387557001, 96097002
English 9-(4-acetoxy-3-(acetoxymethyl)but-1-yl)-2-aminopurine, famciclovir, famciclovir (medication), FAMCICLOVIR, famciclovir [Chemical/Ingredient], Famciclovir, Famciclovir product, Famciclovir (substance), Famciclovir (product)
Spanish famciclovir (producto), famciclovir (sustancia), famciclovir
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Famvir (C0591478)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH C060590
English Famvir, famvir
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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