Human Immunodeficiency Virus Book

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Nelfinavir

Aka: Nelfinavir, Viracept, NFV
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  1. See Also
    1. Anti-Retroviral Therapy
    2. Protease Inhibitor
  2. Mechanism
    1. Protease Inhibitor
  3. Efficacy
    1. May be used as first line agent (potent)
    2. Similar to Ritonavir or Indinavir
  4. Dosing
    1. Take with a meal or light snack
    2. Adult: 750mg po tid or 1250 mg po bid
    3. Child: 20-30 mg/kg tid or 45-55 mg/kg po bid
  5. Adverse Effects
    1. Well tolerated
    2. Diarrhea
  6. References
    1. (1998) Med Lett Drugs Ther 40(1041):115
    2. (2009) Treat Guidel Med Lett 7(78): 11-22
    3. Reust (2011) Am Fam Physician 83(12): 1443-51
Medication Costs
Viracept (on 2/9/2012 at DrugStore.com)
Viracept 250mg Tablets #100 for $292.99 ($2.93/unit)
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information.

Viracept (C0525004)

Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D019888
English viracept, Viracept, Agouron Brand of Nelfinavir Mesylate, Roche Brand of Nelfinavir Mesylate
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Nelfinavir (C0525005)

Definition (CSP) HIV protease inhibitor.
Definition (MSH) A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Definition (NCI) A synthetic antiviral agent. Nelfinavir selectively inhibits human immunodeficiency virus (HIV) protease, thereby preventing cleavage of the gag-pol viral polyprotein and resulting in the release of immature, noninfectious virions. In vivo, this agent exhibits broad tissue distribution compared to related agents. (NCI04)
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D019888
SnomedCT 108706004, 373445001
English Nelfinavir, NELFINAVIR, nelfinavir, Nelfinavir [Chemical/Ingredient], NFV, Nelfinavir (product), Nelfinavir (substance)
Swedish Nelfinavir
Czech nelfinavir
Finnish Nelfinaviiri
Russian NEL'FINAVIR, NELFINAVIR, НЕЛФИНАВИР, НЕЛЬФИНАВИР
Japanese ネルフィナビル
Polish Nelfinawir
Spanish nelfinavir (producto), nelfinavir (sustancia), nelfinavir, Nelfinavir
French Nelfinavir
German Nelfinavir
Italian Nelfinavir
Portuguese Nelfinavir
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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