II. Indications
III. Contraindications
- Giazo is FDA approved for male patients only
IV. Mechanism
- Diazo-Bonded 5-ASA product
- Oral agent converted to active 5-ASA (Mesalamine) by Bacteria within the colon
V. Dosing: Adult (and age>5 years)
- Colazal
- Start 2.25 g orally three times daily for 8 to 12 weeks
- Next 3 to 6 g/day divided three times daily
- Giazo (only male patients)
- Start 3.3 g orally twice daily for 8 weeks
VI. Pharmacokinetics
- Minimal absorption
VII. Efficacy
- Similar, but better tolerated (less Diarrhea) than Olsalazine
VIII. Safety
- Pregnancy Category B
- Unknown safety in Lactation
IX. Resources
- Balsalazide-Colazal (DailyMed)
X. References
- (2022) Treatment of Mild to Moderate Ulcerative Colitis, Presc Lett, #350406
- (2023) Drugs for Inflammatory Bowel Disease, Med Lett Drug Ther 65: 105-12
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Related Studies
| balsalazide (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BALSALAZIDE DISODIUM 750 MG CP | Generic | $0.42 each |