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Postinflammatory Hyperpigmentation
Aka: Postinflammatory Hyperpigmentation
- Definition
- Hyperpigmentation response to inflammation on dark skin
- Causes: Common precipitating lesions
- Acne Vulgaris
- Psoriasis
- Atopic Dermatitis
- Contact Dermatitis
- Lichen Planus
- Signs
- Irregular, dark Macules and patches at sites of injury or inflammation
- Management
- General
- Most effective protocol is to use these agents in combination
- Example
- Hydroquinone 2% with Glycolic Acid 10% applied twice daily
- Tretinoin applied at bedtime
- Bleaching agents
- Hydroquinone (Eldoquin Forte) 2-4% applied twice daily
- Chemical Peels
- Salicylic acid
- Glycolic Acid peel
- Keratolytics
- Azelaic Acid (Azelex) 20% cream applied twice daily
- Tretinoin (Retin-A) 0.025-0.050% applied at bedtime
- Tazarotene (Tazorac) 0.1% cream applied at bedtime
- Course
- Changes can persist for years
- References
- Burns (1997) Dermatol Surg 23(3): 171-5