II. Causes: Papulosquamous

  1. Psoriasis
    1. Red Plaques with overlying white or silver scale
    2. Isolated involvement of the genital skin without Plaques elsewhere would be rare
    3. Distinguish from Bowen Disease (or Penile Cancer in Situ)
    4. Responds to Topical Corticosteroids
  2. Pearly Penile Papules
    1. Small skin-colored, dome-shaped lesions form a ring at the base of the glans penis (at coronal sulcus)
    2. Asymptomatic
    3. Distinguish from Lichen Nitidus, Angiokeratomas

III. Causes: Inflammatory

  1. Lichen Nitidus
    1. Tiny (1 mm), asymptomatic hypopigmented Papules
    2. Often found on non-genital skin
    3. Distinguish from Genital Herpes and pearly penile Papules
  2. Lichen Planus
    1. Pruritic, sore, flat-topped polygonal violaceous Papules
    2. Often found on non-genital skin
    3. Distiniguish from Secondary Syphilis
    4. Responds to Topical Corticosteroids
  3. Lichen Sclerosus of foreskin (Balanitis Xerotica Obliterans)
    1. Cellophane-like hypopigmented, thinned foreskin
    2. May result in Phimosis, Urinary Outflow Obstruction, painful Erections
    3. Pruritus and bleeding may also occur
    4. Distinguish from Scleroderma and Penile Cancer
    5. Responds to Topical Corticosteroids

IV. Causes: Vascular

  1. Angiokeratoma
    1. Red-blue Papules along the margin of the glans penis
    2. May also involve Scrotum, thigh or abdominal skin
    3. Distinguish from Pearly Penile Papules

V. Causes: Infectious

VI. Causes: Neoplastic

  1. Penile Cancer in Situ (Bowen Disease)
    1. Plaque or penile ulcer most typically involving glans penis or foreskin
    2. Broad differential (e.g. Psoriasis, Lichen Sclerosus, Genital Herpes, Secondary Syphilis, Balanitis)
  2. Penile invasive squamous cell cancer
    1. Papulosquamous or exophytic lesions lesions on the penis
    2. Distinguish from condyloma

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Related Studies

Ontology: Penile Neoplasms (C0030849)

Definition (NCI) A benign, borderline, or malignant neoplasm that affects the penis. Representative examples include penile hemangioma, penile intraepithelial neoplasia, and penile carcinoma.
Definition (MSH) Cancers or tumors of the PENIS or of its component tissues.
Concepts Neoplastic Process (T191)
MSH D010412
SnomedCT 126896003
English Neoplasm, Penile, Neoplasms, Penile, Penile Neoplasms, PENILE NEOPL, NEOPL PENILE, PENIS NEOPL, NEOPL PENIS, neoplasm of penis (diagnosis), neoplasm of penis, Penile neoplasms, Neoplasm, Penis, Neoplasms, Penis, Penis Neoplasm, Penis Neoplasms, Penile Neoplasms [Disease/Finding], tumor penis, penile neoplasm, penile neoplasms, penis neoplasm, penis tumour, penis tumors, penis tumor, Penile neoplasm NOS, Penile neoplasm, Tumor of penis, Tumour of penis, Neoplasm of penis (disorder), Neoplasm of penis, Penile Neoplasm, Neoplasm of Penis, Neoplasm of the Penis, Penile Tumor, Tumor of Penis, Tumor of the Penis
Italian Tumore del pene, Tumori del pene, Tumore del pene NAS, Neoplasie del pene
Dutch peniel neoplasma NAO, peniel neoplasma, penisneoplasmata, Penistumor, Penistumoren, Tumor, penis-, Tumoren, penis-
French Tumeur du pénis SAI, Tumeur du pénis, Tumeurs du pénis, Tumeurs péniennes
German Penisneoplasie NNB, Neubildungen des Penis, Penisneubildung, Penistumoren
Portuguese Neoplasia do pénis NE, Neoplasia do pénis, Neoplasias do pénis, Neoplasias Penianas
Spanish Neoplasia peniana NEOM, Tumor del Pene, Tumores Peneanos, Tumor Peneal, Cáncer del Pene, Cáncer Peneal, Tumores del Pene, Cáncer Peneano, Tumor Peneano, Tumores Penianos, Tumor Peniano, neoplasia del pene (trastorno), neoplasia del pene, Neoplasias de pene, Neoplasia peniana, Neoplasias del Pene
Japanese 陰茎新生物NOS, インケイシンセイブツ, インケイシンセイブツNOS, 陰茎新生物, 陰茎腫瘍
Swedish Penistumörer
Finnish Siittimen kasvaimet
Czech Novotvary penisu, Novotvar penisu, Novotvar penisu NOS, penis - novotvary, penis - nádory, nádory penisu
Polish Nowotwory prącia
Hungarian Penis neoplasia, Penis neoplasmák, Penis neoplasia k.m.n.
Norwegian Neoplasmer i penis, Tumorer i penis, Svulster i penis

Ontology: Penile lesion (C0149751)

Concepts Sign or Symptom (T184)
SnomedCT 300513000
English penile lesion (symptom), penile lesion, penile lesion as symptom, Penile lesion, lesions penis, Lesion;penile, penis lesion, lesion penis, lesions penile, Lesion penis, Lesion of penis, Lesion of penis (finding)
Spanish lesión del pene (hallazgo), lesión del pene