Polyarticular Arthritis

Aka: Polyarticular Arthritis, Polyarticular Joint Pain, Polyarthritis, Pauciarticular Arthritis, Oligoarticular Arthritis, Migratory Arthritis, Migratory polyarthritis, Oligoarticular, Oligoarthritis, Pauciarticular, Polyarticular

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II. Causes: Pauciarticular (Oligoarticular) (2-4 joints)

  1. Spondyloarthropathy (especially sacroiliac)
  2. Sarcoidosis (especially ankle)
  3. Rheumatoid Arthritis
  4. Psoriatic Arthritis
  5. Gonococcal Arthritis

III. Causes: Polyarticular (Common)

  1. Large joints
    1. Ankylosing Spondylitis
  2. Small joints
    1. Parvovirus B19
    2. Systemic Lupus Erythematosus
  3. Large and small joints
    1. Osteoarthritis
    2. Rheumatoid Arthritis
    3. Psoriatic Arthritis

IV. Causes: General

  1. Viral Infection
    1. Parvovirus B19
    2. Epstein-Barr Virus
    3. Varicella Zoster
    4. Enterovirus, Adenovirus or Coxsackievirus
    5. Hepatitis B Virus
    6. Human Immunodeficiency Virus (HIV)
    7. Mumps
    8. Rubella
  2. Bacterial Infection
    1. Gonococcal Arthritis
    2. Bacterial Endocarditis
    3. Rheumatic Fever
    4. Whipple's Disease
    5. Salmonella, Shigella or Yersinia Infection
    6. Staphylococcus aureus
    7. Tuberculosis
    8. Lyme Disease
    9. Syphilis
  3. Systemic conditions
    1. Rheumatoid Arthritis
    2. Osteoarthritis
    3. Fibromyalgia
    4. Systemic Lupus Erythematosus
    5. Polymyositis
    6. Polymyalgia Rheumatica
    7. Sarcoidosis
    8. Scleroderma
    9. Sjogren's Syndrome
    10. Behcet's Syndrome
    11. Henoch-Schonlein Purpura
    12. Polyarteritis Nodosa
    13. Granulomatosis with Polyangiitis (previously known as Wegener's Granulomatosis)
    14. Hyperthyroidism
    15. Hypothyroidism
    16. Hyperparathyroidism
  4. Miscellaneous
    1. Cancer (Multiple Myeloma, Metastatic Cancer)
    2. Crystal-induced (e.g. Gout, Pseudogout)
    3. Ankylosing Spondylitis
    4. Psoriatic Arthritis
    5. Inflammatory Bowel Disease
    6. Reiter's Syndrome

V. Causes: Migratory Arthritis

  1. Gonococcal Arthritis
  2. Rheumatic Fever
  3. Sarcoidosis
  4. Systemic Lupus Erythematosus
  5. Lyme Disease
  6. Bacterial Endocarditis
  7. Whipple's Disease

VI. Causes: By Symmetry

  1. Symmetric Polyarthritis
    1. Rheumatoid Arthritis
    2. Systemic Lupus Erythematosus
    3. Psoriatic Arthritis
    4. Osteoarthritis
    5. Scleroderma
    6. Lyme Disease
    7. Rheumatic Fever
    8. Gouty Arthritis
    9. Pseudogout
    10. Liver Disease
  2. Asymmetric Polyarthritis
    1. Spondyloarthropathy (HLA-B27 Disease)
      1. Psoriatic Arthritis
      2. Ankylosing Spondylitis
      3. Reactive Arthritis
      4. Inflammatory Bowel Disease
    2. Gouty Arthritis
    3. Pseudogout
    4. Lyme Disease
    5. Viral Arthritis

VII. Evaluation

  1. See Joint Pain for History, Exam, Labs and Imaging

VIII. References

  1. Klinkhoff (2000) CMAJ 162:1833-8 [PubMed]
  2. Pujalte (2015) Am Fam Physician 92(1):35-41 [PubMed]
  3. Richie (2003) Am Fam Physician 68(6):1151-60 [PubMed]

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Related Studies

Ontology: Polyarthritis (C0162323)

Definition (CSP) inflammation of several joints together.
Concepts Disease or Syndrome (T047)
MSH D001168
ICD9 714.9
ICD10 M06.4 , M05-M14.9, M13.0, M06.49, M05-M14
SnomedCT 202032009, 201817003, 30701005, 41397009, 201763001, 268056006, 203728000, 268053003, 156514009, 417373000, 416956002
English Unspecified inflammatory polyarthropathy, Polyarthritides, Inflamm.polyarthropathy NOS, Inflammatory polyarthropathy NOS, Inflammatory polyarthropathies, Inflamtry polyarthropathies, Polyarthritis, unspecified, [X]Inflammatory polyarthropathies, [X]Inflamtry polyarthropathies, polyarthritis (diagnosis), polyarthritis, Inflamm polyarthrop NOS, Inflammatory polyarthropathy, site unspecified, inflammatory polyarthropathy, polyarthritides, polyarthropathy inflammatory, Inflammatory polyarthropathies (M05-M14), Polyarthritis, Inflammatory polyarthropathy NOS (disorder), Polyarthritis (disorder), Polyarthritis NOS, [X]Inflammatory polyarthropathies (disorder), Polyarthropathy NOS -inflammat, Inflammatory polyarthropathy, NOS, Polyarthritis, NOS, Inflammatory polyarthropathy or polyarthritis NOS, Inflammatory polyarthropathy, Inflammatory polyarthropathy (disorder)
Dutch niet-gespecificeerde inflammatoire polyartropathie, Inflammatoire polyartropathie, Polyartritis, niet gespecificeerd, polyartritis, Polyartritis
French Polyarthropathie inflammatoire non précisée, Polyarthrite
German unspezifische entzuendliche Polyarthropathie, Polyarthritis, Entzuendliche Polyarthropathie, Polyarthritis, nicht naeher bezeichnet
Italian Poliartropatie infiammatorie non specificate, Poliartrite
Portuguese Poliartropatia inflamatória NE, Poliartrite
Spanish Poliartropatía inflamatoria no especificada, Poliartritis, poliartritis, poliartropatía inflamatoria, SAI, [X]poliartropatías inflamatorias (trastorno), poliartritis (concepto no activo), poliartropatía inflamatoria, SAI (trastorno), [X]poliartropatías inflamatorias, poliartropatía inflamatoria (trastorno), poliartropatía inflamatoria
Japanese 多発性関節炎, 詳細不明の炎症性多発性関節障害, ｼｮｳｻｲﾌﾒｲﾉｴﾝｼｮｳｾｲﾀﾊﾂｾｲｶﾝｾﾂｼｮｳｶﾞｲ, ﾀﾊﾂｾｲｶﾝｾﾂｴﾝ
Czech polyartritida, polyarthritis, Blíže neurčená zánětlivá polyartropatie, Polyartritida
Korean 염증성 다발성 관절병증, 상세불명의 다발성 관절염
Hungarian Polyarthritis, Nem meghatározott gyulladásos polyarthropathia
Norwegian Polyartritt
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Migratory polyarthritis (C0240344)

Concepts Disease or Syndrome (T047)
SnomedCT 111211002
English migratory polyarthritis, Migratory polyarthritis (disorder), Migratory polyarthritis, Migratory polyarthritis, NOS
Spanish poliartritis migratoria, poliartritis migratriz (trastorno), poliartritis migratriz
Derived from the NIH UMLS (Unified Medical Language System)

Ontology: Oligoarticular joint involvement (C0427255)

Concepts Finding (T033)
SnomedCT 250098005
English Oligoarticul joint involvement, Pauciartic joint involvement, Few joints involved, Oligoarticular joint involvement, Pauciarticular joint involvement, Oligoarticular joint involvement (finding)
Spanish compromiso oligoarticular (hallazgo), compromiso oligoarticular, compromiso pauciarticular
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Intra-Articular Disorders

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