II. Indications: Autoimmune Conditions

III. Preparations

  1. Older xTNF agents included Thalidomide
  2. Modern xTNF agents (in 2016) are primarily monoclonal antibodies
    1. Examples include Infliximab (Remicade), Adalimumab (Humira) and Etanercept (Enbrel)

V. Prevention

  1. Update Vaccinations prior to starting therapy (Live Vaccines may not be used with xTNF agents)
  2. Screen for Tuberculosis and other infections prior to starting xTNF-a agents
  3. Requires regular lab monitoring depending on agent and condition being treated
  4. Skin Cancer Prevention with regular use of Sunscreen and Self Skin Exam
  5. Patients should seek medical evaluation for acute infectious symptoms while on xTNF agents

VI. References

  1. (2018) Presc Lett 25(7): 40

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Ontology: Anti-tumor necrosis factor alpha drug (C1562242)

Concepts Pharmacologic Substance (T121)
SnomedCT 420693002, 416897008
English Anti-tumor necrosis factor alpha agent (substance), Anti-tumor necrosis factor alpha agent, Anti-tumour necrosis factor alpha agent, Anti-TNF drug, Anti-tumor necrosis factor alpha drug (product), Anti-tumor necrosis factor alpha drug, Anti-tumour necrosis factor alpha drug
Spanish agente con anti-factor de necrosis tumoral alfa (sustancia), agente con FNT-alfa, agente con TNF-alfa, agente con anti-factor de necrosis tumoral alfa, factor de necrosis tumoral alfa (producto), factor de necrosis tumoral alfa