II. Labs: Microscopy - Specific

  1. Monosodium Urate or MSU Crystals: Gout
    1. Needle-shaped
    2. Frequently intracellular
    3. Strongly negatively birefringent
  2. Calcium Pyrophosphate Dihydrate (CPPD): Pseudogout
    1. Rod or rhomboidal shaped
    2. Weakly positive birefringent
  3. Basic Calcium Phosphate (BCP): Calcific periarthritis
    1. Description
      1. Clumps and globules
      2. Non-birefringent
    2. Conditions
      1. Chronic BCP Arthritis
      2. Milwaukee Shoulder-knee syndrome
      3. Mixed BCP-CPPD disease (See above)
      4. Osteoarthritis
      5. Metastatic calcinosis
  4. Calcium Oxalate
    1. Description
      1. Variable bipyramidal morphology
      2. Strongly positively birefringent
    2. Conditions
      1. Chronic dialysis Arthritis
      2. Arthritis of primary oxalosis
  5. Cholesterol Crystals or Lipid Microspheres
    1. Description
      1. Flat, rectangular plates
      2. Notched corners, maltese crosses
      3. Strongly negative birefringent
    2. Conditions
      1. Chronic inflammatory Arthritis
      2. Acute Polyarthritis
  6. Cryoglobulin Crystals: Paraproteinemias
    1. Polygonal Shaped
    2. Positively birefringent

III. Labs: Microscopy - Other Crystals and artifacts

  1. Corticosteroid Crystals: Arthritis flare post injection
    1. Birefringent Crystals
  2. Cystine Crystals: Cystinosis
  3. Xanthine Crystals: Xanthinuria
  4. Charcot-Leyden Crystals: Hypereosinophilic Syndromes
  5. Aluminum phosphate: Hemodialysis
  6. Talc from exam gloves (Artifact)
  7. Apatite (Stained by Alizarin red S)

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Ontology: Microscopy, Polarization (C0026025)

Definition (HL7V3.0) <p>Microscopy, Polarized light</p>
Definition (NCI) Any form of microscopy capable of detecting birefringent objects. Usually performed with a polarizing element below the stage to produce plane polarized light and an analyzer that is set to give total extinction of the background and thus to detect any birefringence.
Definition (MSH) Microscopy using polarized light in which phenomena due to the preferential orientation of optical properties with respect to the vibration plane of the polarized light are made visible and correlated parameters are made measurable.
Concepts Laboratory Procedure (T059)
MSH D008859
HL7 0115
English Light Microscopies, Polarized, Light Microscopy, Polarized, Microscopies, Polarization, Microscopies, Polarized Light, Microscopy, Polarization, Microscopy, Polarized Light, Polarization Microscopies, Polarization Microscopy, Polarized Light Microscopies, Polarized Light Microscopy, Polarization microscopy, Polarizing light microscopy
French Microscopie à lumière polarisée, Microscopie en lumière polarisée, Microscopie de polarisation, Microscopie à polarisation, Microscopie en polarisation
Swedish Polarisationsmikroskopi
Czech mikroskopie polarizační
Finnish Polarisaatiomikroskopia
Italian Microscopia in luce polarizzata, Microscopia polarizzata, Microscopia a luce polarizzata
Polish Mikroskopia polaryzacyjna
Japanese 顕微鏡検査法-偏光, 偏光顕微鏡検査法, 偏光顕微鏡検査
Norwegian Mikroskopi med polarisert lys, Polarisasjonsmikroskopi, Mikroskopi, polarisert lys, Mikroskopi, polarisasjon
German Mikroskopie, Polarisations-, Mikroskopie, polarisiertes Licht, Polarisations-Mikroskopie
Dutch Microscopie, polarisatie-, Polarisatiemicroscopie
Portuguese Microscopia de Luz Polarizada, Microscopia de Polarização
Spanish Microscopía de Luz Polarizada, Microscopía de Polarización

Ontology: Crystal identification of synovial fluid (C0200652)

Concepts Laboratory Procedure (T059)
SnomedCT 75195008
English Crystal identification of synovial fluid, Crystal identification by compensated polarizing lens analysis of synovial fluid, Crystal identification by compensated polarising lens analysis of synovial fluid, Crystal identification of synovial fluid (procedure)
Spanish identificación de cristales en el líquido sinovial (procedimiento), identificación de cristales en el líquido sinovial con luz polarizada, identificación de cristales en el líquido sinovial