Transtubular Potassium Gradient

Aka: Transtubular Potassium Gradient

II. Indications

  1. Hyperkalemia

III. Precautions

  1. Results altered by Hyperkalemia Management
  2. Obtain lab sample prior to intervention if possible
    1. Do not delay treatment in emergent Hyperkalemia

IV. Labs

  1. Serum Potassium and Serum Osmolality
  2. Spot urine for Urine Potassium and Urine Osmolality

V. Calculation: Transtubular Potassium Gradient (TTPG)

  1. TTPG = (Urine K++ x Serum Osm)/(Serum K++ x Urine Osm)
  2. Where K+ is Potassium and Osm is Osmolality

VI. Interpretation: Fractional Excretion of Potassium

  1. TTPG <6-8%: Renal cause of Hyperkalemia
    1. Hypoaldeosteronism suggested by very low TTPG
  2. TTPG >6-8: Extrarenal cause of Hyperkalemia
    1. May also be increased in Chronic Renal Failure

Images: Related links to external sites (from Bing)

These images are a random sampling from a Bing search on the term "Transtubular Potassium Gradient." Click on the image (or right click) to open the source website in a new browser window. Search Bing for all related images

Related Studies

Ontology: Transtubular potassium gradient (C0919835)

Concepts Laboratory Procedure (T059)
Italian Gradiente transtubulare di potassio
Japanese 経尿細管性カリウム勾配, ｹｲﾆｮｳｻｲｶﾝｾｲｶﾘｳﾑｺｳﾊﾞｲ
English Transtubular potassium gradient
Czech Transtubulární draslíkový gradient
Hungarian Transtubularis kálium gradiens
Portuguese Gradiente transtubular de potássio
Spanish Gradiente transtubular de potasio
Dutch transtubulaire kaliumgradiënt
French Gradient trans-tubulaire du potassium
German Transtubulaerer Kaliumgradient
Derived from the NIH UMLS (Unified Medical Language System)

Related Topics in Pathology and Laboratory Medicine

2021 Family Practice Notebook, LLC. Terms | Privacy (EHS) | About | Site Map | Blog

Footer Site Logo