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Ontology:
zaleplon
(C0251504)
Definition (NCI)
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A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.
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Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
MSH |
C085665
|
SnomedCT |
321187004, 116104009, 387012004 |
LNC |
LP30650-3, MTHU015092 |
English |
Acetamide, N-(3-(3-cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-ethyl-, N-(3-(3-cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-ethylacetamide, zaleplon, zaleplon (medication), ZALEPLON, zaleplon [Chemical/Ingredient], Zaleplon (product), Zaleplon (substance), Zaleplon |
Spanish |
zaleplón (producto), zaleplón (sustancia), zaleplón |
Ontology:
Sonata
(C0876170)
Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
|
MSH |
C085665
|
English |
Sonata, sonata, Lundbeck brand of zaleplon, Wyeth brand of zaleplon, Zelepion, AHP brand of zaleplon |