II. Epidemiology
- CDC is reporting 805 Vaping-related severe lung injury cases (and 10 deaths) as of 9/25/2019
III. Mechanisms
- Acute Interstitial Lung Disease
- Related to diacetyl, flavorings, and solvents
- Lipoid Pneumonia (from oil aspiration) with Alveolar Macrophage infiltration
IV. Symptoms
- Fever and chills
- Fatigue
- Non-productive cough
- Dyspnea
- Chest Pain
- Nausea
- Vomiting
- Abdominal Pain
V. Signs
VI. Labs
VII. Imaging
-
Chest XRay
- Infiltrates may be present
- CT Chest
- Ground glass opacities may be present
VIII. Management
-
Hypoxia
- Supplemental Oxygen
- Noninvasive Positive Pressure Ventilation (e.g.BIPAP)
- Endotracheal Intubation
- Adjunctive
- High dose IV Corticosteroids
- Refractory, Critical Illness (e.g. cardiopulmonary collapse)
IX. Resources
X. References
- Tomaszekski (2019) Crit Dec Emerg Med 33(10): 23