II. Background
- Derivations
- LSD semisynthetically derived from ergot alkaloids
- Mescaline naturally derived from peyote
- Psilocybin naturally derived from Psilocybe
- Pharmacokinetics
- LSD (50-400 ug): 8-12 hour duration
- Mescaline (250-600 mg): 8-12 hour duration
- Psilocybin (10-50 mg): 6-8 hour duration
III. Forms or Street Names
- Lysergic Acid Diethylamide (LSD)
- Acid
- Sugar
- Cubes
- Trips
- Windowpane
- Blotter
- Mescaline
- Buttons
- Beans
- Cactus
- Psilocybin
- Magic Mushrooms
- Mushroom
- Los ninos
IV. Signs
- Hyper-suggestible state
V. Signs: Toxicity (Amphetamine-like reaction)
- Hyperthermia
- Rhabdomyolysis
- Severe Hyponatremia
- Cerebral Infarction
VI. Management: Toxicity
- Provide calm and supportive environment
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| Concepts | Mental or Behavioral Dysfunction (T048) |
| English | Hallucinogen Use Disorders |
Ontology: Lysergic Acid Diethylamide (C0024334)
| Definition (MSH) | Semisynthetic derivative of ergot (Claviceps purpurea). It has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover. It is a potent hallucinogen, but the mechanisms of that effect are not well understood. |
| Definition (CSP) | semisynthetic derivative of ergot; it has complex effects on serotonergic systems including antagonism at some peripheral serotonin receptors, both agonist and antagonist actions at central nervous system serotonin receptors, and possibly effects on serotonin turnover; it is a potent hallucinogen and psychotomimetic. |
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) , Hazardous or Poisonous Substance (T131) |
| MSH | D008238 |
| SnomedCT | 15698006 |
| LNC | LP16179-1, MTHU006728 |
| English | Diethylamide, Lysergic Acid, LSD, LSD 25, LSD-25, Lysergic Acid Diethylamide, Lysergide, Acid Diethylamide, Lysergic, lysergic acid diethylamide, Ergoline-8-carboxamide, 9,10-didehydro-N,N-diethyl-6-methyl-, (8beta)-, LSD - D-Lysergic acid, D-Lysergic acid, D-Lysergic Acid Diethylamide, Lysergic Acid Diethylamide [Chemical/Ingredient], lysergic acid diethylamide (LSD), lsd-25, lysergide, Lysergate diethylamide, LYSERGIDE, Lysergic acid diethylamide, Lysergic acid diethylamide (substance), LSD (Drug) |
| Swedish | LSD |
| Czech | diethylamid kyseliny lysergové, LSD |
| Finnish | Lysergihapon dietyyliamidi |
| Russian | LIZERGID, LIZERGINOVOI KISLOTY DIETILAMID, LSD, ЛИЗЕРГИД, ЛИЗЕРГИНОВОЙ КИСЛОТЫ ДИЭТИЛАМИД, ЛСД |
| French | LSD, Lysergide |
| Italian | LSD, Lisergide, LSD-25, Dietilammide dell'acido lisergico |
| Polish | Dietyloamid kwasu lizergowego, Dwuetyloamid kwasu lizergowego |
| Japanese | リセルギド, リセルグ酸ジエチルアミド, リゼルギン酸ジエチルアミド |
| Spanish | dietilamida de ácido lisérgico (sustancia), dietilamida de ácido lisérgico, lisergida, LSD, Lisergida, Dietilamida del Ácido Lisérgico |
| German | LSD, Lysergid, Lysergsäurediethylamid |
| Portuguese | LSD, Dietilamida do Ácido Lisérgico, Lisergida |
Ontology: Mescaline (C0025460)
| Definition (MSH) | Hallucinogenic alkaloid isolated from the flowering heads (peyote) of Lophophora (formerly Anhalonium) williamsii, a Mexican cactus used in Indian religious rites and as an experimental psychotomimetic. Among its cellular effects are agonist actions at some types of serotonin receptors. It has no accepted therapeutic uses although it is legal for religious use by members of the Native American Church. |
| Concepts | Hazardous or Poisonous Substance (T131) , Organic Chemical (T109) |
| MSH | D008635 |
| SnomedCT | 229008008, 373780001, 83192000 |
| LNC | LP17987-6, MTHU003041 |
| English | Mescaline, Trimethoxyphenethylamine, Benzeneethanamine, 3,4,5-trimethoxy-, 3,4,5-Trimethoxyphenethylamine, Mescalin substance of abuse, Peyote extract, Mescalin, mescaline in any form, Mescaline [Chemical/Ingredient], mescalin, mescaline, Mescalin substance of abuse (substance), Mescaline (product), Mescaline (substance) |
| Swedish | Meskalin |
| Czech | meskalin |
| Finnish | Meskaliini |
| Russian | MEZKALIN, MESKALIN, PEIOT, TRIMETOKSIFENETILAMIN, МЕЗКАЛИН, МЕСКАЛИН, ПЕЙОТ, ТРИМЕТОКСИФЕНЕТИЛАМИН |
| Japanese | メズカリン, メスカリン, メッカリン, ペヨーテ, トリメトキシフェネチルアミン |
| Croatian | MESKALIN |
| Polish | Meskalina |
| Spanish | mescalina, sustancia de abuso (sustancia), extracto de peyote, mescalina, sustancia de abuso, Peyotl, mescalina (producto), mescalina (sustancia), mescalina, Mescalina, Trimetoxifenetil Amina |
| Portuguese | Peyote, Peyotl, Mescalina, Trimetoxifenetilamina |
| French | Mescaline |
| German | Mescalin, Trimethoxyphenethylamin |
| Italian | Mescalina |
