II. Indications

III. Preparations

  1. Oxytocin (Pitocin)
    1. Onset in 3 to 5 minutes
    2. Intramuscular: 10-20 units
    3. Intravenous: 40 units/liter at 250 cc/hour
  2. Ergotamine (Methergine)
    1. Dosing: 0.2 mg IM or PO every 6-8 hours
    2. Onset in 2 to 5 minutes
    3. Contraindications
      1. Hypertension
      2. Pregnancy Induced Hypertension
      3. Hypersensitivity
  3. Prostaglandin (Hemabate)
    1. Dosing: 0.25mg Intramuscular or Intra-Myometrium
    2. Onset <5 minutes
    3. Administer every 15 minutes to maximum of 2 mg
  4. Misoprostol 600 mcg PO or PR
    1. Khan (2003) Obstet Gynecol 101:968-74 [PubMed]

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Ontology: Oxytocics (C0030094)

Definition (MSH) Drugs that stimulate contraction of the myometrium. They are used to induce LABOR, OBSTETRIC at term, to prevent or control postpartum or postabortion hemorrhage, and to assess fetal status in high risk pregnancies. They may also be used alone or with other drugs to induce abortions (ABORTIFACIENTS). Oxytocics used clinically include the neurohypophyseal hormone OXYTOCIN and certain prostaglandins and ergot alkaloids. (From AMA Drug Evaluations, 1994, p1157)
Definition (CSP) class of drugs that promote rapid labor by, like the hormone oxytocin, stimulating uterine myometrial contractions.
Concepts Pharmacologic Substance (T121)
MSH D010120
SnomedCT 424999005, 20208007, 410937004
English Oxytocics, Agents, Oxytocic, Drugs, Oxytocic, Oxytocic Agents, Oxytocic Drugs, Stimulants, Uterine, Uterine Stimulants, Oxytocic hormone, Oxytocic preparation, Oxytocic preparation (product), OXYTOCICS, oxytocics, oxytocics (medication), [GU600] OXYTOCICS, uterine stimulant, oxytocic, uterine stimulants, Oxytocic preparation, NOS, Oxytocic preparation (substance), Oxytocic agent (substance), Oxytocic agent
French Médicaments ocytociques, Agents ocytociques, Ocytociques
Swedish Oxytociska medel
Czech oxytocika
Finnish Synnytystä jouduttavat lääkkeet
Spanish oxitócico (producto), preparación oxitócica (producto), oxitócico, preparación oxitócica, preparado oxitócico, preparado ocitócico (producto), preparado ocitócico, Efecto Oxitócico, preparado ocitócico (sustancia), agente oxitócico (sustancia), agente oxitócico, Estimulantes Uterinos, Oxitócicos
Italian Agenti ossitocici, Stimolanti uterini, Farmaci ossitocici, Ossitocici
Polish Leki oksytotyczne, Oksytotyki
Japanese 子宮収縮剤, 子宮刺激剤, 分娩促進剤, 陣痛促進剤, 陣痛促進薬, 子宮収縮薬, 陣痛促進用薬剤
Portuguese Efeito Ocitócico, Estimulantes Uterinos, Ocitócicos
German Uterine Stimulanzien, Wehenanregende Substanzen