II. Indications

  1. Start prior to conception of pregnancy

III. Preparations: Key components (Higher doses than standard Vitamins)

  1. Folate 400 mcg or 600 Dietary Folate Equivalents or DFE (See Folic Acid for references)
    1. Dose is higher if increased risk
      1. Folate 4000 mcg started 3 months before pregnancy (continue for first trimester)
        1. Prior Neural Tube Defect
        2. Use of Valproate or Carbamazepine
      2. Folate 800 mcg daily (1200 Dietary Folate Equivalents or DFE)
        1. Anti-epileptic drugs other than Valproate or Carbamazepine
    2. Most important component in Prenatal Vitamins
    3. Reduces Neural Tube Defects by 50% at conception
      1. Spina bifida
      2. Anencephaly
    4. Reduced fetal risk of Cleft Lip and Palate by 25-50%
    5. Reduces conotruncal heart defects by 43%
  2. Calcium 250 mg
    1. Diet needs supply 750 mg/day to total 1000 mg/day
    2. See Calcium Supplementation
  3. Iron Supplementation (27 to 30 mg elemental iron)
    1. Higher iron contents are not well absorbed
  4. Iodine 150 mcg

IV. Preparations: Other Components

  1. Magnesium Supplementation (320 mg Magnesium)
  2. Vitamin C 65 mg
  3. Zinc 25 mg (See Zinc for references)
    1. Increases birth weight and Head Circumference
    2. Results in birth at later Gestational age
    3. Results in shorter hospital stay
  4. Vitamin A 800 mcg (8,000 IU)
    1. Should not exceed 1000 mcg (10,000 IU)
    2. Teratogen at higher doses
  5. Vitamin D 10 mcg
  6. Vitamin E 10 mcg
  7. B Vitamins
    1. Vitamin B6 2.2 mcg
    2. Thiamine
    3. Riboflavin

V. Non-Vitamin Components

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Related Studies

Cost: Medications

prenatal vitamin (on 5/17/2017 at Medicaid.Gov Survey of pharmacy drug pricing)

Ontology: Prenatal vitamin (C0772413)

Definition (NCI) A vitamin enriched supplement containing higher doses for specific nutrients such as folic acid, intended for women before, during and after pregnancy and also during their lactating phase.
Concepts Pharmacologic Substance (T121) , Vitamin (T127)
SnomedCT 400572001
English prenatal vitamins (medication), prenatal vitamins, vitamin prenatal, vitamins prenatal, prenatal vitamin, Prenatal Vitamin, prenatal vitamins with calcium, Prenatal vitamin (product), Prenatal vitamin, Prenatal Vitamins
Spanish vitamina prenatal (producto), vitamina prenatal