II. Causes
III. Findings: Symptoms and Signs (Mnemonic: SLUDgE + Killer Bs, or DUMBELLS)
- Sludge
- Killer B's
- Bronchospasm
- Bronchorrhea
- Bradycardia (muscarinic)
- Tachycardia may occur with nicotinic toxicity
- Other
- Miosis (pinpoint pupils)
IV. Findings: Symptoms and Signs: Other (not covered by mnemonic)
- Anxiety or Agitation
- Seizures
- Coma
- Muscle fasciculations
- Flaccid Paralysis (including respiratory muscles)
V. Diagnostics
VI. Management
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| Definition (MSH) | Drugs that mimic the effects of parasympathetic nervous system activity. Included here are drugs that directly stimulate muscarinic receptors and drugs that potentiate cholinergic activity, usually by slowing the breakdown of acetylcholine (CHOLINESTERASE INHIBITORS). Drugs that stimulate both sympathetic and parasympathetic postganglionic neurons (GANGLIONIC STIMULANTS) are not included here. |
| Concepts | Pharmacologic Substance (T121) |
| MSH | D010277 |
| SnomedCT | 19581007, 372668005 |
| English | Parasympathomimetics, Agents, Parasympathomimetic, Drugs, Parasympathomimetic, Parasympathomimetic Agents, Parasympathomimetic Drugs, parasympathomimetic agent, parasympathomimetics, parasympathomimetics (medication), parasympathomimetic drugs, parasympathomimetic drug, parasympathomimetic agents, parasympathomimetic, PARASYMPATHOMIMETICS, Parasympathomimetic agents, Parasympathomimetic, Parasympathomimetic agent (product), Parasympathomimetic agent (substance), Parasympathomimetic agent, Parasympathomimetic agent, NOS |
| Swedish | Parasympatomimetika |
| Czech | parasympatomimetika, cholinomimetika |
| Finnish | Parasympatomimeetit |
| French | Médicaments parasympathomimétiques, Agents parasympathomimétiques, Parasympathomimétiques |
| Russian | PARASIMPATOMIMETIKI, ПАРАСИМПАТОМИМЕТИКИ |
| Croatian | PARASIMPATOMIMETICI |
| Polish | Leki parasympatykomimetyczne |
| Japanese | 副交感神経興奮薬, 副交感神経作動剤, 副交感神経作動薬, 副交感神経様作動物質, 副交感神経様作動薬, 副交感神経様作用薬物 |
| Spanish | Efecto Parasimpaticomimético, agente parasimpaticomimético (producto), agente parasimpaticomimético (sustancia), agente parasimpaticomimético, Parasimpaticomiméticos |
| Portuguese | Efeito Parassimpatomimético, Parassimpatomiméticos |
| German | Parasympathikomimetika |
| Italian | Parasimpatomimetici |
Ontology: Cholinomimetics (C0242892)
| Concepts | Pharmacologic Substance (T121) |
| MSH | D018678 |
| French | Médicaments acétylcholinomimétiques, Agents cholinomimétiques, Acétylcholinomimétiques, Médicaments cholinomimétiques, Cholinomimétiques |
| Spanish | Colinomiméticos |
| German | Cholinomimetika |
| Italian | Colinomimetici |
| English | cholinomimetics, cholinomimetic, Cholinomimetics |
| Portuguese | Colinomiméticos |
Ontology: Cholinergic Agents (C0242893)
| Definition (MSH) | Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of ACETYLCHOLINE, and drugs that affect the survival of cholinergic neurons. The term cholinergic agents is sometimes still used in the narrower sense of MUSCARINIC AGONISTS, although most modern texts discourage that usage. |
| Definition (CSP) | drug used for its actions in stimulating cholinergic systems. |
| Concepts | Pharmacologic Substance (T121) |
| MSH | D018678 |
| SnomedCT | 19581007 |
| English | Agents, Cholinergic, Cholinergic Agents, cholinergic agent, Acetylcholine Agents, Agents, Acetylcholine, Cholinergic Drugs, Drugs, Cholinergic, cholinergic agents, cholinergic drugs, cholinergics, cholinergic drug, Cholinergics, Cholinergic agent, Cholinergic agent, NOS |
| French | Médicaments cholinergiques, Cholinergiques, Agents acétylcholinergiques, Agents cholinergiques |
| Swedish | Kolinerga medel |
| Czech | cholinergní látky |
| Finnish | Kolinergiset lääkkeet |
| Italian | Agenti dell'acetilcolina, Colinergici, Farmaci colinergici, Sostanze colinergiche |
| Russian | KHOLINERGICHESKIE SREDSTVA, KHOLINOPOZITIVNYE SREDSTVA, ATSETILKHOLINOVYE SREDSTVA, KHOLINOMIMETICHESKIE SREDSTVA, MUSKARINOVYE SREDSTVA, KHOLINOMIMETIKI, NIKOTINOVYE SREDSTVA, АЦЕТИЛХОЛИНОВЫЕ СРЕДСТВА, МУСКАРИНОВЫЕ СРЕДСТВА, НИКОТИНОВЫЕ СРЕДСТВА, ХОЛИНЕРГИЧЕСКИЕ СРЕДСТВА, ХОЛИНОМИМЕТИКИ, ХОЛИНОМИМЕТИЧЕСКИЕ СРЕДСТВА, ХОЛИНОПОЗИТИВНЫЕ СРЕДСТВА |
| Croatian | Not Translated[Cholinergic Agents] |
| Polish | Czynniki cholinergiczne, Środki pobudzające układ przywspółczulny |
| Portuguese | Colinérgicos, Acetilcolínicos, Agentes Colinérgicos, Agentes Muscarínicos, Agentes de Acetilcolina, Efeito Colinérgico, Agentes Nicotínicos |
| Spanish | Colinérgicos, Acetilcolínicos, Agentes Nicotínicos, Efecto Colinérgico, Agentes de Acetilcolina, Agentes Muscarínicos, Agentes Colinérgicos, agente colinérgico, droga colinérgica |
| Norwegian | Not Translated[Cholinergic Agents] |
| German | Acetylcholin-Analoga, Cholinergika |
Ontology: Poisoning by parasympathomimetic drug (C0274702)
| Concepts | Injury or Poisoning (T037) |
| ICD9 | 971.0 |
| SnomedCT | 212680000, 61356009 |
| English | CHOLINERGIC SYNDROME, PARASYMPATHOMIMETIC SYNDROME, Cholinergic poisoning NOS, parasympathomimetic toxicity (diagnosis), parasympathomimetic toxicity, Syndrome cholinergic, Parasympathomimetic syndrome, Syndrome parasympathomimetic, Pois-parasympathomimetic, Poisoning by parasympathomimetics (cholinergics), Cholinergic poisoning NOS (disorder), Cholinergic poisoning, Parasympathomimetic poisoning, Cholinergic syndrome, Poisoning by cholinergic drug, Poisoning by parasympathomimetic drug (disorder), Poisoning by parasympathomimetic drug, Poisoning by cholinergic drug, NOS, Poisoning by parasympathomimetic drug, NOS, Poisoning by cholinergics, Poisoning by parasympathomimetics |
| Italian | Sindrome colinergica, Sindrome parasimpaticomimetica, Avvelenamento da parasimpaticomimetici (colinergici) |
| Dutch | parasympathicomimetisch syndroom, syndroom cholinerg, syndroom parasympathomimetisch, vergiftiging door parasympaticomimetica (cholinergica), cholinerg syndroom |
| French | Syndrome parasympathomimétique, SYNDROME CHOLINERGIQUE, SYNDROME PARASYMPATHOMIMETIQUE, Intoxication par parasympathomimétiques (cholinergiques), Syndrome cholinergique |
| German | Syndrom, Parasympathomimetikum, Parasympathomimetikum-Syndrom, Syndrom cholinerg, CHOLINERGES SYNDROM, PARASYMPATHIKOMIMETISCHE SYMPTOMA, Vergiftung durch Parasympathomimetika (Cholinergika), cholinerges Syndrom |
| Portuguese | Síndrome parassimpaticomimética, Síndrome parassimpaticomémitica, SINDROME COLINERGICO, SINDROME PARASIMPATICOMIMETICO, Intoxicação por parassimpaticomiméticos (colinérgicos), Síndrome colinérgica |
| Spanish | Síndrome parasimpaticomimético, COLINERGICO, SINDROME, PARASIMPATICOMIMETICO, SINDROME, Intoxicación por parasimpaticomiméticos (colinérgicos), intoxicación colinérgica, SAI (trastorno), intoxicación colinérgica, SAI, intoxicación por droga colinérgica (trastorno), intoxicación por droga colinérgica, intoxicación por droga parasimpaticomimética, síndrome colinérgico, Síndrome colinérgico |
| Japanese | コリン作動性症候群, 副交感神経作動性症候群, ｺﾘﾝｻﾄﾞｳｾｲｼｮｳｺｳｸﾞﾝ, ﾌｸｺｳｶﾝｼﾝｹｲｻﾄﾞｳｾｲｼｮｳｺｳｸﾞﾝ, 副交感神経作用薬（コリン作用薬）中毒, ﾌｸｺｳｶﾝｼﾝｹｲｻﾖｳﾔｸｺﾘﾝｻﾖｳﾔｸﾁｭｳﾄﾞｸ |
| Czech | Cholinergní syndrom, Parasympatomimetický syndrom, Syndrom parasympatomimetický, Otrava parasympatomimetiky (cholinergiky) |
| Hungarian | Parasympathomimeticus syndroma, Parasympathomimetikus syndroma, Cholinergiás syndroma, Cholinerg syndroma, Paraszimpatomimetikumok (kolinerg szerek) által okozott mérgezés |
