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Gonadotoxin

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Gonadotoxin, Medications that Impair Male Fertility

  • See Also
  1. Infertility
  2. Impotence due to Medication
  • Causes
  • Drug or toxin use
  1. Nicotine or Tobacco use or Passive Smoke Exposure
  2. Alcohol Abuse
  3. Anabolic Steroids
  4. Antiandrogens
  5. Cocaine
  6. Marijuana use
  7. Opioids
  8. Toxin exposure
    1. Heavy metal exposure
    2. Organic solvents and Pesticides
    3. Radiation exposure
    4. Alkylating Agents
  • Causes
  • Other medications
  1. Allopurinol
  2. Colchicine
  3. Chemotherapy
  4. Cimetidine
  5. Corticosteroids
  6. Cyclosporine
  7. Diltiazem
  8. Erythromycin
  9. Gentamicin
  10. Methotrexate
  11. Neomycin
  12. Nifedipine
  13. Nitrofurantoin
  14. Opioids
  15. Tetracycline
  16. Spironolactone
  17. Sulfasalazine
  18. Ketoconazole
  • Causes
  • Possible Effects (need further study)
  1. Ibuprofen
    1. May decrease sex hormones
    2. However has not been shown to cause inferility, lower testosterone or decreased Sperm Count
    3. Kristensen Proc (2018) Natl Acad Sci U S A 115(4):E715-E724 +PMID: 29311296 [PubMed]
  • References
  1. Kolettis (2003) Am Fam Physician 67(10):2165-72 [PubMed]