Pharm

Cyclobenzaprine

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Cyclobenzaprine, Flexeril

  • See Also
  1. Antispasmodic Skeletal Muscle Relaxant
  • Indications
  1. Acute back or Neck Pain interfering with sleep despite Analgesics
  • Class
  1. Antispasmodic Skeletal Muscle Relaxant
  • Dosing
  1. Start: 5 mg orally at bedtime (5 mg is as effective as 10 mg and with less sedation)
  2. Maximum: 10 mg orally three times daily (primarily at bedtime for pain interfering with sleep)
  • Contraindications
  1. Older patients
    1. See Medications to Avoid in Older Adults
  2. Seizure disorder (if concurrently on Tramadol)
  3. Glaucoma
  4. Cardiac arrhythmia
  5. Congestive Heart Failure
  6. Recent Myocardial Infarction
  • Efficacy
  1. See Antispasmodic Skeletal Muscle Relaxant
  • Adverse effects
  1. See Antispasmodic Skeletal Muscle Relaxant for precautions
  2. Common: Anticholinergic
    1. Drowsiness
    2. Dry Mouth
    3. Urinary Retention
    4. Increased Intraocular Pressure
  3. Rare
    1. Arrhythmia
    2. Seizure
    3. Myocardial Infarction