Pharm

Calcitonin

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Calcitonin

  1. Weak Osteoporosis Management alternative for women not on Estrogen Replacement
  2. Painful Vertebral osteoporotic Fracture
  • Efficacy
  1. Not as effective as Estrogen Replacement
  2. Reduces Vertebral Fractures 30-60% for >2 years
  3. Increases BMD of spine 3% in osteoporotic women
  • Preparations
  1. Calcitonin-Salmon
    1. Dosing: 100 IU SQ/IM daily ($195/mo)
  2. Miacalcin
    1. Dosing: 200 IU (1 spray) intranasally daily in alternating nares ($50/mo)
  • Precautions
  1. Anaphylaxis risk (use test dose in clinic)
  2. Possible increased risk of cancer
  • Adverse Effects
  1. Skin Flushing
  2. Skin rash
  3. Nausea
  4. Dizzy