Pharm
Adalimumab
search
Adalimumab
, Humira
See Also
Etanercept
(
Enbrel
)
Infliximab
(
Remicade
)
Indications
Severe active
Rheumatoid Arthritis
refractory to
DMARDs
Contraindications
Chronic or acute infection
Concurrent use of
Interleukin-1 Receptor Antagonist
Anakinra
(
Kineret
)
Mechanism
Monoclonal Antibody
Human antitumor Necrosis Factor alpha
Similar to
Infliximab
and
Etanercept
Dosing
Every other week: 40 mg SC
Adverse Effects
Immunosuppression
Use caution in any patient prone to infection
Headache
Rash
Hypertension
Hyperlipidemia
Injection site inflammation
Gastrointestinal upset
Cost
Two 40 mg vials: $1200 (in 2003)
References
(2003) Lexi-Comp Drug Database
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