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Hypervolemic Hypoosmolar Hyponatremia

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Hypervolemic Hypoosmolar Hyponatremia

  • Pathophysiology
  1. Edematous State reduces effective circulating volume
  2. Decreased flow to nephron diluting segment
  3. Stimulates ADH release
  • Management
  1. See Hyponatremia Management
  2. Salt and water restriction
  3. Optimize Cardiac Output
  4. Consider Dialysis for Renal Insufficiency
  5. Consider Diuretics
  • References
  1. Kone in Tisher (1993) Nephrology, p. 87-100
  2. Levinsky in Wilson (1991) Harrison's IM, p. 281-84
  3. Rose (1989) Acid-Base and Electrolytes, p. 601-38
  4. Braun (2015) Am Fam Physician 91(5): 299-307 [PubMed]