Glomerulus

Isolated Proteinuria

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Isolated Proteinuria

  • Diagnosis
  1. Proteinuria <2000 mg/day without other abnormality
    1. No Hypertension
    2. No Renal Insufficiency
    3. No other urologic or renal abnormalities
  2. Diagnosis made on clinical criteria (no specific study)
  • Labs
  1. Urine Microscopy normal
  2. Urine Protein 24 Hour collection
    1. Less than 2000 mg protein excretion per day
  3. Split 24 Hour Urine Protein collection
    1. Urine Protein >50 mg for 8 hours supine
    2. Contrast with Orthostatic Proteinuria
  4. Renal Function tests
    1. Normal Creatinine Clearance
  • Differential Diagnosis
  • Monitoring
  1. Consider Nephrology Consultation
  2. Blood Pressure every 6 months
  3. Urinalysis every 6 months
  4. Creatinine Clearance every 6 months
  • Prognosis
  1. Renal Insufficiency risk: 20% in 10 years