Pharm
Antidepressant
search
Antidepressant
, Depression Medication
See Also
Major Depression
Psychiatric Medications in Pregnancy
Medical Management of Depression
Antepartum Depression
Types
Serotonin Norepinephrine Reuptake Inhibitor
s (
SNRI
)
Tricyclic Antidepressant
s
Tertiary amines:
Amitriptyline
(
Elavil
)
Secondary amines:
Nortriptyline
(
Pamelor
)
Other
Venlafaxine
(
Effexor
)
Tetracyclic: rarely use
Serotonin Norepinephrine Reuptake Inhibitor
s (
SNRI
)
Venlafaxine
(
Effexor
)
Desvenlafaxine
(
Pristiq
)
Duloxetine
(
Cymbalta
)
Levomilnacipran (Fetzima)
Selective Serotonin Reuptake Inhibitor
s (
SSRI
)
Paroxetine
(
Paxil
)
Fluoxetine
(
Prozac
)
Sertraline
(
Zoloft
)
Fluvoxamine
(
Luvox
)
Citalopram
(
Celexa
)
Escitalopram
(
Lexapro
)
Vortioxetine (Brintellix)
New in 2013, similar to generic
SSRI
s, with more
Nausea
at 10x the cost
Norepinephrine Dopamine Reuptake Inhibitor
(
NDRI
)
Bupropion
(
Wellbutrin
,
Zyban
)
Serotonin Antagonist and Reuptake Inhibitor
(
SARI
)
Nefazodone
(
Serzone
)
Trazodone
(
Desyrel
)
Norepinephrine Antagonist Serotonin Antagonist
(NASA)
Mirtazapine
(
Remeron
)
Monoamine Oxidase Inhibitor
(
MAO inhibitor
)
Isocarboxazid (Marplan)
Phenelzine
(
Nardil
)
Tranylcypromine
(
Parnate
)
Efficacy
Number Needed to Treat
for significant improvement of
Major Depression
Tricyclic Antidepressant
s (TCA): 7-16
Selective Serotonin Reuptake Inhibitor
s (
SSRI
): 7-8
Arroll (2009) Cochrane Database Syst Rev (3): CD007954 [PubMed]
Adverse Effects
See
Antidepressant Adverse Effects
See
Antepartum Depression
Complications
Serotonin Syndrome
Antidepressant Withdrawal
Resources
Patient Education
Information from your Family Doctor
http://www.familydoctor.org/handouts/012.html
References
Kovich (2015) Am Fam Physician 92(2): 94-100 [PubMed]
Bhatia (1997) Am Fam Physician 55(5):1683-94 [PubMed]
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