Analgesic
Nalmefene
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Nalmefene
, Revex
Indications
Narcotic Toxicity
requiring frequent
Naloxone
dosing
Precautions
Do not use as first line agent for
Narcotic Toxicity
Risk of severe
Narcotic Withdrawal
Pharmacokinetics
Long acting
Opioid
antagonist
Duration: 4-8 hours
Dosing
Opioid Overdose
Initial: 0.5 mg per 70 kg person IV
Later: 1 mg per 70 kg IV prn 5 min after initial dose
Narcotic
dependent: 0.1 mg per 70 kg test dose
Post-operative
Narcotic
reversal
Dose: 0.25 ug/kg IV q2-5 minutes
Maximum: 1 ug/kg total dose
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