Alternative

Blue Cohosh

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Blue Cohosh, Caulophyllum thalictroides

  • Current use
  1. Oxytocin-like agent used in Labor Augmentation
  • Contraindications
  1. Hypertension
  2. Underlying Cardiovascular disease
  • Mechanism
  1. Perennial plant growing in North America
    1. Member of Berberidaceae family
  2. Active ingredients
    1. Glycoside: Caulosaponin
    2. Alkaloid: Methylcysteine (nicotine-like compound)
      1. Increases Blood Pressure
      2. Stimulates uterine contractions
      3. Stimulates gastrointestinal motility
      4. Stimulates coronary Vasoconstriction
  • Efficacy
  1. No studies supporting efficacy or safety