Pharm

RhoGAM

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RhoGAM, RHO Immune globulin

  • Indications
  1. Prevention of Rh Sensitization in Rh negative mother
  • Timing
  1. Uterine bleeding or Trauma
  2. Routine scheduled dosing for Rh negative mother
    1. Gestational age: 28 weeks
    2. Postpartum
  • Dose
  1. Uterine bleeding
    1. RhoGAM dose based on Kleihauer-Betke
    2. Give 300 ug per 30 ml fetal whole blood or 15 ml pRBC
  2. No Uterine bleeding
    1. Gestation under 13 weeks: RhoGAM 50 ug IM
    2. Gestation over 13 weeks: RhoGAM 300 ug IM