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Fetal Hydantoin Syndrome

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Fetal Hydantoin Syndrome

  • See Also
  • Definition
  1. Congenital syndrome due to in-utero Phenytoin exposure
  • Epidemiology
  1. Incidence: <10% of exposed fetuses
  • Signs
  1. Microcephaly
  2. Growth Delay
  3. Mental Retardation and Developmental Delay
  4. Craniofacial dysmorphic features
    1. Flat nasal bridge
    2. Epicanthic folds
    3. Prominent upper lip over wide mouth
  5. Distinguishing characteristics
    1. Nail and distal phalanx hypoplasia
    2. Hypertelorism
  • Differential Diagnosis
  • References
  1. Gabbe (2002) Obstetrics, Churchill, p. 225
  2. Ellenhorn (1997) Medical Toxicology, Williams, p. 606