Pharm

Levetiracetam

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Levetiracetam, Keppra

  • Indications
  1. Seizure Prophylaxis
  2. Second ot thrid line agent in Status Epilepticus
  • Dosing
  1. Start: 500 to 1000 mg/day (max 4000 mg/day) divided twice daily
  2. Titrate every 2 weeks
  3. Target serum concentration: 12 to 46 mcg/ml
  • Adverse Effects
  1. Agitation
  2. Anxiety
  3. Depressed mood
  4. Dizziness
  5. Fatigue
  6. Irritability
  7. Rash
  8. Somnolence
  • References
  1. Liu (2017) Am Fam Physician 96(2): 87-96 [PubMed]